GO Report

Basic Info
ID GO:0007169
Name transmembrane receptor protein tyrosine kinase signaling pathway
Type biological process
No. of Genes in BDgene  16
Source Pathway by Database Search

PBA Result

GO related genes in BDgene (count: 16)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend) Evidence[PMID]
ERBB4 erb-b2 receptor tyrosine kinase 4 2q33.3-q34 2(1/1/0) IDA[10353604]
DOK5 docking protein 5 20q13.2 1(1/0/0) IEA
PTPRT protein tyrosine phosphatase, receptor type, T 20q12-q13 2(0/1/1) IMP[16973135]
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 15q24-q25 2(2/0/0) IDA[23027130]
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 9q22.1 3(1/1/1) TAS
NRG1 neuregulin 1 8p12 15(10/5/0) IDA[7514177]
ITK IL2-inducible T-cell kinase 5q31-q32 1(1/0/0) IBA
BDKRB2 bradykinin receptor B2 14q32.1-q32.2 1(1/0/0) TAS[10653985]
TNK2 tyrosine kinase, non-receptor, 2 3q29 1(0/1/0) IBA
ROR1 receptor tyrosine kinase-like orphan receptor 1 1p31.3 1(0/0/1) IEA
BDNF brain-derived neurotrophic factor 11p14.1 37(24/12/1) IBA
FYN FYN proto-oncogene, Src family tyrosine kinase 6q21 1(1/0/0) IBA
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 18p11 3(1/2/0) TAS
JAK1 Janus kinase 1 1p32.3-p31.3 1(0/1/0) IBA
ROR2 receptor tyrosine kinase-like orphan receptor 2 9q22 1(0/1/0) IEA
NGF nerve growth factor (beta polypeptide) 1p13.1 2(1/1/0) IBA; TAS