Gene Report

Basic Info
Approved Symbol PTPRT
Symbol Alias RPTPrho, KIAA0283
Approved Name protein tyrosine phosphatase, receptor type, T
Location 20q12-q13
Position chr20:42072752-43189970, -1
External Links HGNC: 9682
Entrez Gene: 11122
Ensembl: ENSG00000196090
UCSC: uc010ggj.3
No. of Studies 2 (Positive: 0; Negative: 1; trend: 1)
Overlap with SZ? NO
Overlap with MDD? YES
Gene related studies (count: 2)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Sklar, P.,2011 SNP: rs6102917 No significant association was observed. Negative Comment on Study
Green, E. K.,2012 SNP: rs6102947 BD ImmunoChip:P-value = 0.2562,OR = 1.189;ImmunoChip, PGC-BD combined data:P-balue = 0.0000513,OR = 1.289 Suggestive association was found. Trend Comment on Study
Gene functional annotation
Gene related GO terms (count: 16)

GO terms by PBA (count: 4)

GO terms by database search (count: 12)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 1)

Related other genetic factors
Gene related SNPs (count: 15)

Literature-origin SNPs (count: 2)

LD-proxies (count: 13)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

Overlap with MDD from cross-disorder studies (count: 0)

Overlap with MDD from candidate gene intersection analysis (count: 1)

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Region: chr20:42072752..43189970 View in gBrowse
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