Search SNP
Search Gene
Search CNV
Search Haplotype
Search Other Variant
Search Region
Search Pathway
Search Study
GO Report
Basic Info
| ID | GO:0007169 |
|---|---|
| Name | transmembrane receptor protein tyrosine kinase signaling pathway |
| Type | biological process |
| No. of Genes in BDgene | 16 |
| Source | Pathway by Database Search |
PBA Result
GO related genes in BDgene (count: 16)
| Approved Symbol | Approved Name | Location | No. of Studies (Positive/Negative/Trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 2q33.3-q34 | 2(1/1/0) | IDA[10353604] |
| DOK5 | docking protein 5 | 20q13.2 | 1(1/0/0) | IEA |
| PTPRT | protein tyrosine phosphatase, receptor type, T | 20q12-q13 | 2(0/1/1) | IMP[16973135] |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 | 15q24-q25 | 2(2/0/0) | IDA[23027130] |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 9q22.1 | 3(1/1/1) | TAS |
| NRG1 | neuregulin 1 | 8p12 | 15(10/5/0) | IDA[7514177] |
| ITK | IL2-inducible T-cell kinase | 5q31-q32 | 1(1/0/0) | IBA |
| BDKRB2 | bradykinin receptor B2 | 14q32.1-q32.2 | 1(1/0/0) | TAS[10653985] |
| TNK2 | tyrosine kinase, non-receptor, 2 | 3q29 | 1(0/1/0) | IBA |
| ROR1 | receptor tyrosine kinase-like orphan receptor 1 | 1p31.3 | 1(0/0/1) | IEA |
| BDNF | brain-derived neurotrophic factor | 11p14.1 | 37(24/12/1) | IBA |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 6q21 | 1(1/0/0) | IBA |
| ADCYAP1 | adenylate cyclase activating polypeptide 1 (pituitary) | 18p11 | 3(1/2/0) | TAS |
| JAK1 | Janus kinase 1 | 1p32.3-p31.3 | 1(0/1/0) | IBA |
| ROR2 | receptor tyrosine kinase-like orphan receptor 2 | 9q22 | 1(0/1/0) | IEA |
| NGF | nerve growth factor (beta polypeptide) | 1p13.1 | 2(1/1/0) | IBA; TAS |