SNP Report

Basic Info
Name rs4774370 dbSNP Ensembl
Location chr15:60601232 - 60601232(1)
Variant Alleles T/C
Ancestral Allele T
Minor Allele C
Minor Allele Frequence 0.157548
Functional Annotation intron_variant; NMD_transcript_variant; non_coding_transcript_variant.
Consequence to Transcript intron_variant(ENST00000261523, ENST00000309157, ENST00000335670, ENST00000551975, ENST00000557822, ENST00000558235, ENST00000559824, ENST00000560004); NMD_transcript_variant(ENST00000551975); non_coding_transcript_variant(ENST00000557822, ENST00000558235, ENST00000559824, ENST00000560004)
No. of Studies 1 (Positive: 1; Negative: 0; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? YES

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Soria, V.,2010 X2-tests: allele P-value = 0.95, Model Recessive,...... X2-tests: allele P-value = 0.95, Model Recessive, genotype P-value = 0.031, OR(95%CI)=2.26 (1.09-4.67) More... Significant association was found in BD. Significant association was found in BD. Positive

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
RORA RAR-related orphan receptor A 15q21-q22 3(2/1/0)

SNPs in LD with rs4774370 (count: 0) View in gBrowse (chr15:60601232..60601232 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Soria, V.,2010 X2-tests:allele P-value > 0.05, genotype P-value > 0.05 in all model No significant association was observed. Negative