SNP Report

Basic Info

Name	rs4774370 dbSNP Ensembl
Location	chr15:60601232 - 60601232(1)
Variant Alleles	T/C
Ancestral Allele	T
Minor Allele	C
Minor Allele Frequence	0.157548
Functional Annotation	intron_variant; NMD_transcript_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000261523, ENST00000309157, ENST00000335670, ENST00000551975, ENST00000557822, ENST00000558235, ENST00000559824, ENST00000560004); NMD_transcript_variant(ENST00000551975); non_coding_transcript_variant(ENST00000557822, ENST00000558235, ENST00000559824, ENST00000560004)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	YES

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Soria, V.,2010			X²-tests: allele P-value = 0.95, Model Recessive,...... X²-tests: allele P-value = 0.95, Model Recessive, genotype P-value = 0.031, OR(95%CI)=2.26 (1.09-4.67) More...	Significant association was found in BD. Significant association was found in BD.	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
RORA	RAR-related orphan receptor A	15q21-q22	3(2/1/0)

SNPs in LD with rs4774370 (count: 0) View in gBrowse (chr15:60601232..60601232 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Soria, V.,2010	X²-tests:allele P-value > 0.05, genotype P-value > 0.05 in all model	No significant association was observed.	Negative