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KEGG Pathway Report
Basic Info
| ID | hsa04730 |
|---|---|
| Name | Long-term depression |
| No. of Genes in BDgene | 15 |
| Source | Pathway by PBA |
PBA Result
| Pathway Name in Paper | Source | Reference | Data Set | Tool | Result Parameters | Result Link |
|---|---|---|---|---|---|---|
| Long-term depression | PBA paper | Chang, S., 2015 | group B | i-GSEA4GWAS v2, GenGen | FDR=0.1464 (B) by i-GSEA4GWAS v2; FDR=0.058 (B) by GenGen |
Pathway related genes in BDgene (count: 15)
| Approved Symbol | Approved Name | Location | No. of Studies (Positive/Negative/Trend)  |
|---|---|---|---|
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) | 22q13.1 | 2(1/1/0) |
| GRIA1 | glutamate receptor, ionotropic, AMPA 1 | 5q33 | 2(2/0/0) |
| NOS1 | nitric oxide synthase 1 (neuronal) | 12q24.22 | 8(2/5/1) |
| NOS3 | nitric oxide synthase 3 (endothelial cell) | 7q36 | 2(1/1/0) |
| CRHR1 | corticotropin releasing hormone receptor 1 | 17q21.31 | 4(2/2/0) |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide | 22q11.1-q11.2 | 1(1/0/0) |
| GRIA3 | glutamate receptor, ionotropic, AMPA 3 | Xq25 | 1(0/1/0) |
| GNAS | GNAS complex locus | 20q13.2-q13.3 | 1(0/1/0) |
| PLA2G1B | phospholipase A2, group IB (pancreas) | 12q24.31 | 4(1/3/0) |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | 12q23.2 | 1(1/0/0) |
| CRH | corticotropin releasing hormone | 8q13 | 2(1/1/0) |
| PPP2R2C | protein phosphatase 2, regulatory subunit B, gamma | 4p16.1 | 2(1/1/0) |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 | 7p22.3 | 1(1/0/0) |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | 3p21.31 | 1(0/1/0) |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 8p21.2 | 1(0/1/0) |