BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

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GO Report

Basic Info

ID	GO:0030165
Name	PDZ domain binding
Type	molecular function
No. of Genes in BDgene	16
Source	Pathway by PBA

PBA Result

Pathway Name in Paper	Source	Reference	Data Set	Tool	Result Parameters	Result Link
GO: 0030165: PDZ domain binding	PBA paper	Askland, K.,2009	NIMH	Fisher's exact test	Results given for gene sets with P < 0.05 from the NIMH PBA; Molecular function

GO related genes in BDgene (count: 16)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)	Evidence[PMID]
GRM7	glutamate receptor, metabotropic 7	3p26-p25	3(2/1/0)	NAS[12052533]
GRIK2	glutamate receptor, ionotropic, kainate 2	6q16.3	3(1/1/1)	IEA
GRIA1	glutamate receptor, ionotropic, AMPA 1	5q33	2(2/0/0)	ISS
DLG3	discs, large homolog 3 (Drosophila)	Xq13.1	1(0/1/0)	IEA
GJA1	gap junction protein, alpha 1, 43kDa	6q22.31	1(1/0/0)	IEA
CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	2p21	1(0/1/0)	IDA[23209302]
SRR	serine racemase	17p13	1(0/1/0)	IPI[16314870]
EXOC4	exocyst complex component 4	7q31	1(0/0/1)	IEA
SNTG2	syntrophin, gamma 2	2p25	1(0/0/1)	IPI[17292328]
SLC9A3	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3	5p15.3	1(1/0/0)	ISS
LNX1	ligand of numb-protein X 1, E3 ubiquitin protein ligase	4q12	1(1/0/0)	IEA
FZD3	frizzled class receptor 3	8p21	1(0/1/0)	IPI[18256285]
GRIK5	glutamate receptor, ionotropic, kainate 5	19q13.2	2(1/0/1)	IEA
FZD2	frizzled class receptor 2	17q21.1	1(0/1/0)	IPI[19388021]
PARK2	parkin RBR E3 ubiquitin protein ligase	6q25.2-q27	1(1/0/0)	IPI[17512523]
CIT	citron rho-interacting serine/threonine kinase	12q24.23	2(1/1/0)	IDA[17474715]