BDgene

Gene Report

Basic Info
Approved Symbol GRIK5
Previous Symbol GRIK2
Symbol Alias GluK5, KA2
Approved Name glutamate receptor, ionotropic, kainate 5
Location 19q13.2
Position chr19:41998321-42069498, -1
External Links HGNC: 4583
Entrez Gene: 2901
Ensembl: ENSG00000105737
UCSC: uc002osj.2
No. of Studies 2 (Positive: 1; Negative: 0; trend: 1)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 2)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Yosifova, A.,2011 SNP: rs8099939 Suggestive association of this gene was found. Trend Comment on Study
Gratacos, M.,2009 SNP: rs10414815 Strong associations of GRIK5 to bipolar disorder have been identified。 Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 26)

GO terms by PBA (count: 6)

GO terms by database search (count: 20)


Gene related KEGG pathways (count: 1)

KEGG pathways by PBA (count: 0)

KEGG pathways by database search (count: 1)


Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 6)

Related other genetic factors
Gene related SNPs (count: 3)

Literature-origin SNPs (count: 3)

LD-proxies (count: 0)


Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with SZ from candidate gene intersection analysis (count: 1)


Gene relationship with MDD

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Region: chr19:41998321..42069498 View in gBrowse
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