SNP Report

Basic Info

Name	rs3734254 dbSNP Ensembl
Location	chr6:35427233 - 35427233(1)
Variant Alleles	C/T
Ancestral Allele	C
Minor Allele	C
Minor Allele Frequence	0.306709
Functional Annotation	3_prime_UTR_variant; downstream_gene_variant.
Consequence to Transcript	3_prime_UTR_variant(ENST00000311565, ENST00000360694, ENST00000418635, ENST00000448077); downstream_gene_variant(ENST00000337400)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Zandi, P. P, 2008 (a)	T/C		Allelic P-value = 0.03 Allelic P-value = 0.03		Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
PPARD	peroxisome proliferator-activated receptor delta	6p21.2	1(1/0/0)

SNPs in LD with rs3734254 (count: 5) View in gBrowse (chr6:35400132..35427841 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs7751481	intron_variant	0.825[CEU]; 0.813[TSI]
rs1040436	intron_variant	0.825[CEU]; 0.813[TSI]
rs1883322	intron_variant	0.825[CEU]; 0.813[TSI]
rs1053049	3_prime_UTR_variant; downstream_gene_variant	0.917[TSI]
rs2267667	intron_variant	0.825[CEU]; 0.844[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)