SNP Report

Basic Info

Name	rs9462082 dbSNP Ensembl
Location	chr6:35418264 - 35418264(1)
Variant Alleles	A/G
Ancestral Allele	G
Minor Allele	A
Minor Allele Frequence	0.133187
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000311565, ENST00000337400, ENST00000360694, ENST00000418635, ENST00000448077)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Zandi, P. P, 2008 (a)	G/A		Allelic P-value < .001 Allelic P-value < .001	Additional genotyping in PPARD yielded 4 SNPs in 1 haplotype...... Additional genotyping in PPARD yielded 4 SNPs in 1 haplotype block that were significantly associated with bipolar disorder, the most significant being rs9462082. Exploratory analyses revealed significant evidence for interactions of rs9462082 with poor functioning on the Global Assessment Scale. More...	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
PPARD	peroxisome proliferator-activated receptor delta	6p21.2	1(1/0/0)

SNPs in LD with rs9462082 (count: 7) View in gBrowse (chr6:35401307..35435008 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs760783	downstream_gene_variant	0.875[CEU]; 1.0[TSI]
rs9470015	intron_variant	0.936[CEU]
rs7749160	downstream_gene_variant	0.939[CEU]; 1.0[TSI]
rs2267668	intron_variant	0.883[CEU]; 0.865[TSI]
rs4713858		0.936[CEU]; 0.828[TSI]
rs2267669	intron_variant	0.883[CEU]; 0.865[TSI]
rs2038067	intron_variant	0.873[CEU]; 0.888[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)