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KEGG Pathway Report
Basic Info
| ID | hsa05221 |
|---|---|
| Name | Acute myeloid leukemia |
| No. of Genes in BDgene | 7 |
| Source | Pathway by PBA |
PBA Result
| Pathway Name in Paper | Source | Reference | Data Set | Tool | Result Parameters | Result Link |
|---|---|---|---|---|---|---|
| Acute myeloid leukemia | PBA paper | Chang, S., 2015 | group A | i-GSEA4GWAS v2,SRT | FDR=0.2093 (A) by i-GSEA4GWAS v2; FDR=0.044 (A) by SRT |
Pathway related genes in BDgene (count: 7)
| Approved Symbol | Approved Name | Location | No. of Studies (Positive/Negative/Trend)  |
|---|---|---|---|
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 5q13.1 | 1(1/0/0) |
| TCF7L1 | transcription factor 7-like 1 (T-cell specific, HMG-box) | 2p11.2 | 1(0/1/0) |
| TCF4 | transcription factor 4 | 18q21.1 | 6(1/5/0) |
| PIK3CG | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma | 7q22 | 1(0/0/1) |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 10q25.3 | 1(1/0/0) |
| PPARD | peroxisome proliferator-activated receptor delta | 6p21.2 | 1(1/0/0) |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 14q32.33 | 3(3/0/0) |