BDgene

KEGG Pathway Report

Basic Info
ID hsa04720
Name Long-term potentiation
No. of Genes in BDgene  13
Source Pathway by PBA

PBA Result
Pathway Name in Paper Source Reference Data Set Tool Result Parameters Result Link
Long-term potentiation PBA paper Chang, S., 2015 group B i-GSEA4GWAS v2, GenGen FDR=0.0482 (B) by i-GSEA4GWAS v2; FDR=0.003 (B) by GenGen
Long-term potentiation i-GSEA analysis Smith, E. N., Mol Psychiatry, 2009 dbGaP GAIN EA i-GSEA by using i-GSEA4GWAS P-value< 0.001, FDR=0.044969697 Link in i-GSEA4GWAS

Pathway related genes in BDgene (count: 13)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
GRIA1 glutamate receptor, ionotropic, AMPA 1 5q33 2(2/0/0)
CREBBP CREB binding protein 16p13.3 1(0/1/0)
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 16p13.2 1(1/0/0)
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme 8p21.3 1(0/1/0)
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 9q34.3 3(2/1/0)
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 12p13.1 8(4/4/0)
ATF4 activating transcription factor 4 22q13.1 1(1/0/0)
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 12p13.3 20(17/3/0)
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D 19q13.33 1(1/0/0)
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 10q22.2 2(1/1/0)
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 5q32 2(1/1/0)
ADCY8 adenylate cyclase 8 (brain) 8q24 4(2/1/1)
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1p36.1 1(0/1/0)