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KEGG Pathway Report
Basic Info
| ID | hsa04210 |
|---|---|
| Name | Apoptosis |
| No. of Genes in BDgene | 12 |
| Source | Pathway by PBA |
PBA Result
| Pathway Name in Paper | Source | Reference | Data Set | Tool | Result Parameters | Result Link |
|---|---|---|---|---|---|---|
| Apoptosis | PBA paper | Peng, G., 2010 | WTCCC | hypergeometric test (Fisher's exact test), Sidak's method, Simes' method, Simes/FDR method | Simes/FDR P-value=0.0141222 |
Pathway related genes in BDgene (count: 12)
| Approved Symbol | Approved Name | Location | No. of Studies (Positive/Negative/Trend)  |
|---|---|---|---|
| IL1B | interleukin 1, beta | 2q14 | 1(1/0/0) |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 5q13.1 | 1(1/0/0) |
| BCL2 | B-cell CLL/lymphoma 2 | 18q21.3 | 2(0/2/0) |
| PPP3CC | protein phosphatase 3, catalytic subunit, gamma isozyme | 8p21.3 | 1(0/1/0) |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 22q12.3 | 2(1/1/0) |
| PIK3CG | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma | 7q22 | 1(0/0/1) |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | 1p36.1 | 1(0/1/0) |
| NGF | nerve growth factor (beta polypeptide) | 1p13.1 | 2(1/1/0) |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 17q24.2 | 1(1/0/0) |
| TNF | tumor necrosis factor | 6p21.3 | 4(2/2/0) |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 14q32.33 | 3(3/0/0) |
| PPP3CB | protein phosphatase 3, catalytic subunit, beta isozyme | 10q22.2 | 2(1/1/0) |