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GO Report
Basic Info
| ID | GO:0000187 |
|---|---|
| Name | activation of MAPK activity |
| Type | biological process |
| No. of Genes in BDgene | 14 |
| Source | Pathway by Database Search |
PBA Result
GO related genes in BDgene (count: 14)
| Approved Symbol | Approved Name | Location | No. of Studies (Positive/Negative/Trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| MAP2K6 | mitogen-activated protein kinase kinase 6 | 17q | 1(0/1/0) | TAS |
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | 6q25.1 | 1(0/0/1) | TAS |
| TLR4 | toll-like receptor 4 | 9q33.1 | 1(1/0/0) | ISS |
| DRD4 | dopamine receptor D4 | 11p15.5 | 13(1/12/0) | IDA[15755724] |
| GRM4 | glutamate receptor, metabotropic 4 | 6p21.3 | 2(2/0/0) | IDA[15102938] |
| PLA2G1B | phospholipase A2, group IB (pancreas) | 12q24.31 | 4(1/3/0) | ISS[15528384] |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 | 15q24-q25 | 2(2/0/0) | IDA[23027130] |
| P2RX7 | purinergic receptor P2X, ligand gated ion channel, 7 | 12q24 | 9(2/7/0) | IEA |
| MAPK10 | mitogen-activated protein kinase 10 | 4q22-q23 | 1(0/1/0) | TAS[7826642] |
| ADORA2B | adenosine A2b receptor | 17p12 | 1(1/0/0) | TAS[10101031] |
| IL1B | interleukin 1, beta | 2q14 | 1(1/0/0) | IDA[10748004] |
| TNF | tumor necrosis factor | 6p21.3 | 4(2/2/0) | IDA[10748004] |
| PROK2 | prokineticin 2 | 3p21.1 | 1(0/1/0) | TAS[12728244] |
| CHRNA7 | cholinergic receptor, nicotinic, alpha 7 (neuronal) | 15q13.3 | 4(2/2/0) | IDA[10771023] |