BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

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Region Report

Basic Info

Region Name	6q21
Chromosome Position	chr6:105000000-114200000
No. of Studies (Positive/Negative/Trend)	4(1/2/1)

Region related studies (count: 4)

Reference	Markers	Statistical Values	Author Comments	Result Category
Fanous, A. H.,2012	rs9285394	Linkage analysis: Maximum NPL (nearest maximum LOD) = 3.1(1....... Linkage analysis: Maximum NPL (nearest maximum LOD) = 3.1(1.74) More...	No significant linkage was found in this region. No significant linkage was found in this region.	Negative
Cheng, R.,2006	D6S474	Two point parametric linkage analysis: LOD = 0.35, theta = 0...... Two point parametric linkage analysis: LOD = 0.35, theta = 0.05, Model BP1, rec More...	No significant linkage was found in this region. No significant linkage was found in this region.	Negative
Schulze, T. G.,2004	D6S474	Affected Sibling-Pair Linkage Analysis: Paternal LOD = 0.33,...... Affected Sibling-Pair Linkage Analysis: Paternal LOD = 0.33, Maternal LOD = 1.92, Gender-Combined LOD = 1.98 More...	Suggestive linkage was found in this region. Suggestive linkage was found in this region.	Trend
Badner, J. A.,2012	rs1046943	Merlin analysis: affection status model 1: Pairs-LOD = 3.4 Merlin analysis: affection status model 1: Pairs-LOD = 3.4	Significant linkage was found in this region. Significant linkage was found in this region.	Positive

Region related genes (count: 13)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
LACE1	lactation elevated 1	6q22.1	1(1/0/0)
RFPL4B	ret finger protein-like 4B	6q21	1(1/0/0)
SEC63	SEC63 homolog (S. cerevisiae)	6q21	1(1/0/0)
DDO	D-aspartate oxidase	6q22.1	1(1/0/0)
NR2E1	nuclear receptor subfamily 2, group E, member 1	6q21	1(1/0/0)
SCML4	sex comb on midleg-like 4 (Drosophila)	6q21	1(0/1/0)
SLC22A16	solute carrier family 22 (organic cation/carnitine transporter), member 16	6q21	1(1/0/0)
FIG4	FIG4 phosphoinositide 5-phosphatase	6q21	1(1/0/0)
POPDC3	popeye domain containing 3	6q21	1(1/0/0)
FOXO3	forkhead box O3	6q21	1(1/0/0)
BVES	blood vessel epicardial substance	6q21	1(1/0/0)
PREP	prolyl endopeptidase	6q22	2(2/0/0)
FYN	FYN proto-oncogene, Src family tyrosine kinase	6q21	1(1/0/0)

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Region: chr6:105000000..114200000 View in gBrowse