KEGG Pathway Report

Basic Info
ID hsa00230
Name Purine metabolism
No. of Genes in BDgene  12
Source Pathway by PBA

PBA Result
Pathway Name in Paper Source Reference Data Set Tool Result Parameters Result Link
Purine metabolism PBA paper Chen, L., 2009 WTCCC Prioritizing Risk Pathways fusing SNPs and pathways (PRP) risk score=1.00

Pathway related genes in BDgene (count: 12)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 14q21-q22 1(1/0/0)
PRIM2 primase, DNA, polypeptide 2 (58kDa) 6p12-p11.1 1(0/0/1)
NME7 NME/NM23 family member 7 1q24.2 1(0/1/0)
ADCY8 adenylate cyclase 8 (brain) 8q24 4(2/1/1)
ADSSL1 adenylosuccinate synthase like 1 14q32.33 1(0/1/0)
PDE4D phosphodiesterase 4D, cAMP-specific 5q12 1(0/1/0)
NT5C2 5'-nucleotidase, cytosolic II 10q24.32 2(2/0/0)
ADCY2 adenylate cyclase 2 (brain) 5p15.3 2(1/1/0)
PDE4B phosphodiesterase 4B, cAMP-specific 1p31 3(1/2/0)
ADCY9 adenylate cyclase 9 16p13.3 2(1/1/0)
ADSL adenylosuccinate lyase 22q13.1 2(1/1/0)
PDE10A phosphodiesterase 10A 6q26 1(0/1/0)