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BioCarta Pathway Report
Basic Info
| ID | nfatPathway |
|---|---|
| Name | NFAT and Hypertrophy of the heart (Transcription in the broken heart) |
| No. of Genes in BDgene | 11 |
| Source | Pathway by Database Search |
Pathway related genes in BDgene (count: 11)
| Approved Symbol | Approved Name | Location | No. of Studies (Positive/Negative/Trend)  |
|---|---|---|---|
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 5q13.1 | 1(1/0/0) |
| CREBBP | CREB binding protein | 16p13.3 | 1(0/1/0) |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | 12q23.2 | 1(1/0/0) |
| PPP3CC | protein phosphatase 3, catalytic subunit, gamma isozyme | 8p21.3 | 1(0/1/0) |
| GSK3B | glycogen synthase kinase 3 beta | 3q13.3 | 8(0/8/0) |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 1q42.2 | 1(1/0/0) |
| PIK3CG | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma | 7q22 | 1(0/0/1) |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | 1p36.1 | 1(0/1/0) |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 17q24.2 | 1(1/0/0) |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 14q32.33 | 3(3/0/0) |
| PPP3CB | protein phosphatase 3, catalytic subunit, beta isozyme | 10q22.2 | 2(1/1/0) |