GO Report

Basic Info
ID GO:0005764
Name lysosome
Type cellular component
No. of Genes in BDgene  16
Source Pathway by PBA

PBA Result
Pathway Name in Paper Source Reference Data Set Tool Result Parameters Result Link
LYSOSOME i-GSEA analysis Smith, E. N., Mol Psychiatry, 2009 dbGaP GAIN EA i-GSEA by using i-GSEA4GWAS P-value< 0.001, FDR=0.023142857 Link in i-GSEA4GWAS

GO related genes in BDgene (count: 16)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend) Evidence[PMID]
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 10q21 17(13/3/1) IEA
HPS4 Hermansky-Pudlak syndrome 4 22q12.1 1(1/0/0) IDA[12663659]
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase 4q32.2 1(0/1/0) IDA[14722266]
ADRB2 adrenoceptor beta 2, surface 5q31-q32 1(1/0/0) TAS[9507004]
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1 22q13.33 5(1/4/0) ISS
CTSH cathepsin H 15q25.1 1(0/0/1) IDA[15196205]
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1p36 1(0/0/1) IDA[20381137]
TPP1 tripeptidyl peptidase I 11p15.4 1(1/0/0) IDA[15317752]; IMP[9295267]
ACE angiotensin I converting enzyme 17q23.3 5(2/3/0) IDA[11076943]
GJA1 gap junction protein, alpha 1, 43kDa 6q22.31 1(1/0/0) IEA
CPQ carboxypeptidase Q 8q22.2 1(0/1/0) ISS
EPDR1 ependymin related 1 7p14.1 1(1/0/0) IEA
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 4q13 1(0/0/1) IEA
RPTOR regulatory associated protein of MTOR, complex 1 17q25.3 2(1/1/0) IDA[20381137]
APOE apolipoprotein E 19q13.31 1(1/0/0) IEA
TYR tyrosinase 11q14.3 1(0/1/0) TAS[11092760]