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GO Report
Basic Info
| ID | GO:0005764 |
|---|---|
| Name | lysosome |
| Type | cellular component |
| No. of Genes in BDgene | 16 |
| Source | Pathway by PBA |
PBA Result
| Pathway Name in Paper | Source | Reference | Data Set | Tool | Result Parameters | Result Link |
|---|---|---|---|---|---|---|
| LYSOSOME | i-GSEA analysis | Smith, E. N., Mol Psychiatry, 2009 | dbGaP GAIN EA | i-GSEA by using i-GSEA4GWAS | P-value< 0.001, FDR=0.023142857 | Link in i-GSEA4GWAS |
GO related genes in BDgene (count: 16)
| Approved Symbol | Approved Name | Location | No. of Studies (Positive/Negative/Trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 10q21 | 17(13/3/1) | IEA |
| HPS4 | Hermansky-Pudlak syndrome 4 | 22q12.1 | 1(1/0/0) | IDA[12663659] |
| MARCH1 | membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase | 4q32.2 | 1(0/1/0) | IDA[14722266] |
| ADRB2 | adrenoceptor beta 2, surface | 5q31-q32 | 1(1/0/0) | TAS[9507004] |
| MLC1 | megalencephalic leukoencephalopathy with subcortical cysts 1 | 22q13.33 | 5(1/4/0) | ISS |
| CTSH | cathepsin H | 15q25.1 | 1(0/0/1) | IDA[15196205] |
| MTOR | mechanistic target of rapamycin (serine/threonine kinase) | 1p36 | 1(0/0/1) | IDA[20381137] |
| TPP1 | tripeptidyl peptidase I | 11p15.4 | 1(1/0/0) | IDA[15317752]; IMP[9295267] |
| ACE | angiotensin I converting enzyme | 17q23.3 | 5(2/3/0) | IDA[11076943] |
| GJA1 | gap junction protein, alpha 1, 43kDa | 6q22.31 | 1(1/0/0) | IEA |
| CPQ | carboxypeptidase Q | 8q22.2 | 1(0/1/0) | ISS |
| EPDR1 | ependymin related 1 | 7p14.1 | 1(1/0/0) | IEA |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 4q13 | 1(0/0/1) | IEA |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 17q25.3 | 2(1/1/0) | IDA[20381137] |
| APOE | apolipoprotein E | 19q13.31 | 1(1/0/0) | IEA |
| TYR | tyrosinase | 11q14.3 | 1(0/1/0) | TAS[11092760] |