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GO Report
Basic Info
| ID | GO:0019904 |
|---|---|
| Name | protein domain specific binding |
| Type | molecular function |
| No. of Genes in BDgene | 24 |
| Source | Pathway by PBA |
PBA Result
| Pathway Name in Paper | Source | Reference | Data Set | Tool | Result Parameters | Result Link |
|---|---|---|---|---|---|---|
| PROTEIN DOMAIN SPECIFIC BINDING | i-GSEA analysis | From NIMH | Thematically Organized Psychosis (TOP) Study | i-GSEA by using i-GSEA4GWAS | P-value< 0.001, FDR=0.0388 | Link in i-GSEA4GWAS |
| GO: 0019904: protein domain speciWc binding | PBA paper | Askland, K.,2009 | NIMH | Fisher's exact test | Results given for gene sets with P < 0.05 from the NIMH PBA; Molecular function |
GO related genes in BDgene (count: 24)
| Approved Symbol | Approved Name | Location | No. of Studies (Positive/Negative/Trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| DRD3 | dopamine receptor D3 | 3q13.3 | 19(4/15/0) | IEA |
| CHMP1B | charged multivesicular body protein 1B | 18p11.21 | 2(0/2/0) | IPI[17928862] |
| DDC | dopa decarboxylase (aromatic L-amino acid decarboxylase) | 7p12.1 | 5(2/3/0) | IEA |
| PICK1 | protein interacting with PRKCA 1 | 22q13.1 | 1(0/1/0) | ISS |
| ARRB2 | arrestin, beta 2 | 17p13 | 1(1/0/0) | IEA |
| ATP1A1 | ATPase, Na+/K+ transporting, alpha 1 polypeptide | 1p13 | 1(1/0/0) | IEA |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | 22q13.2 | 1(1/0/0) | IEA |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | 22q12.1-q13.1 | 3(2/0/1) | ISS |
| NEFL | neurofilament, light polypeptide | 8p21.2 | 1(0/1/0) | IEA |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 10q26 | 1(1/0/0) | IEA |
| TH | tyrosine hydroxylase | 11p15.5 | 16(4/12/0) | IEA |
| MED12 | mediator complex subunit 12 | Xq13 | 1(0/1/0) | IPI[11984006] |
| THRA | thyroid hormone receptor, alpha | 17q21.1 | 1(1/0/0) | IPI[9653119] |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 18p11.2 | 1(1/0/0) | IPI[20178991] |
| MTOR | mechanistic target of rapamycin (serine/threonine kinase) | 1p36 | 1(0/0/1) | IEA |
| BASP1 | brain abundant, membrane attached signal protein 1 | 5p15.1 | 1(0/0/1) | IPI[14701728] |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 9q33.3 | 1(0/1/0) | IPI[12411443] |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 17p13.3 | 1(0/1/0) | IEA |
| GABRR3 | gamma-aminobutyric acid (GABA) A receptor, rho 3 (gene/pseudogene) | 3q11.2 | 1(1/0/0) | IEA |
| NDE1 | nudE neurodevelopment protein 1 | 16p13.11 | 1(1/0/0) | IEA |
| TGM2 | transglutaminase 2 | 20q12 | 1(1/0/0) | IEA |
| TACC3 | transforming, acidic coiled-coil containing protein 3 | 4p16.3 | 1(1/0/0) | IEA |
| PRKCZ | protein kinase C, zeta | 1p36.33-p36.2 | 1(1/0/0) | IEA |
| IL1B | interleukin 1, beta | 2q14 | 1(1/0/0) | IPI[16575408] |