BDgene

GO Report

Basic Info
ID GO:0019904
Name protein domain specific binding
Type molecular function
No. of Genes in BDgene  24
Source Pathway by PBA

PBA Result
Pathway Name in Paper Source Reference Data Set Tool Result Parameters Result Link
PROTEIN DOMAIN SPECIFIC BINDING i-GSEA analysis From NIMH Thematically Organized Psychosis (TOP) Study i-GSEA by using i-GSEA4GWAS P-value< 0.001, FDR=0.0388 Link in i-GSEA4GWAS
GO: 0019904: protein domain speciWc binding PBA paper Askland, K.,2009 NIMH Fisher's exact test Results given for gene sets with P < 0.05 from the NIMH PBA; Molecular function

GO related genes in BDgene (count: 24)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend) Evidence[PMID]
DRD3 dopamine receptor D3 3q13.3 19(4/15/0) IEA
CHMP1B charged multivesicular body protein 1B 18p11.21 2(0/2/0) IPI[17928862]
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 7p12.1 5(2/3/0) IEA
PICK1 protein interacting with PRKCA 1 22q13.1 1(0/1/0) ISS
ARRB2 arrestin, beta 2 17p13 1(1/0/0) IEA
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1p13 1(1/0/0) IEA
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 22q13.2 1(1/0/0) IEA
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta 22q12.1-q13.1 3(2/0/1) ISS
NEFL neurofilament, light polypeptide 8p21.2 1(0/1/0) IEA
TACC2 transforming, acidic coiled-coil containing protein 2 10q26 1(1/0/0) IEA
TH tyrosine hydroxylase 11p15.5 16(4/12/0) IEA
MED12 mediator complex subunit 12 Xq13 1(0/1/0) IPI[11984006]
THRA thyroid hormone receptor, alpha 17q21.1 1(1/0/0) IPI[9653119]
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 18p11.2 1(1/0/0) IPI[20178991]
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1p36 1(0/0/1) IEA
BASP1 brain abundant, membrane attached signal protein 1 5p15.1 1(0/0/1) IPI[14701728]
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 9q33.3 1(0/1/0) IPI[12411443]
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 17p13.3 1(0/1/0) IEA
GABRR3 gamma-aminobutyric acid (GABA) A receptor, rho 3 (gene/pseudogene) 3q11.2 1(1/0/0) IEA
NDE1 nudE neurodevelopment protein 1 16p13.11 1(1/0/0) IEA
TGM2 transglutaminase 2 20q12 1(1/0/0) IEA
TACC3 transforming, acidic coiled-coil containing protein 3 4p16.3 1(1/0/0) IEA
PRKCZ protein kinase C, zeta 1p36.33-p36.2 1(1/0/0) IEA
IL1B interleukin 1, beta 2q14 1(1/0/0) IPI[16575408]