BDgene

SNP Report

Basic Info
Name rs3744805 dbSNP Ensembl
Location chr17:40092101 - 40092101(1)
Variant Alleles C/T
Ancestral Allele C
Minor Allele T
Minor Allele Frequence 0.294928
Functional Annotation 3_prime_UTR_variant; downstream_gene_variant; intron_variant.
Consequence to Transcript 3_prime_UTR_variant(ENST00000450525); downstream_gene_variant(ENST00000246672, ENST00000546243); intron_variant(ENST00000264637, ENST00000394121, ENST00000584985)
No. of Studies 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? YES

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Kishi, T., 2008 (b) A > G G Hardy-Weinberg equilibrium P value=0.152, genotypic P value=...... Hardy-Weinberg equilibrium P value=0.152, genotypic P value=0.222, allelic P value=0.313 for bipolor disorder. Hardy-Weinberg equilibrium P value=0.328, genotypic P value=0.342, allelic P value=0.292 for bipolor I disorder. Hardy-Weinberg equilibrium P value=0.275, genotypic P value=0.473, allelic P value=0.693 for bipolor II disorder. More... Negative

SNP related genes (count: 2)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
THRA thyroid hormone receptor, alpha 17q21.1 1(1/0/0)
NR1D1 nuclear receptor subfamily 1, group D, member 1 17q11.2 6(2/4/0)

SNPs in LD with rs3744805 (count: 1) View in gBrowse (chr17:40092101..40096407 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 1)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 1)
Reference Statistical Result Description Result Category
Kishi, T., 2008 (b) Hardy-Weinberg equilibrium P value=0.783, genotypic P value=0.833, allelic P value=0.768 for MDD. No significant association was found with major depressive disorder. Negative