BDgene

SNP Report

Basic Info
Name rs10937823 dbSNP Ensembl
Location chr4:7478695 - 7478695(1)
Variant Alleles C/T
Ancestral Allele C
Minor Allele T
Minor Allele Frequence 0.144768
Functional Annotation intron_variant; non_coding_transcript_variant.
Consequence to Transcript intron_variant(ENST00000329016, ENST00000507866, ENST00000511199); non_coding_transcript_variant(ENST00000511199)
No. of Studies 3 (Positive: 2; Negative: 0; Trend: 1)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 3)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Takata, A.,2011(a) T/C Fisher's exact test: allele P-value = 0.3432, genotype P-val...... Fisher's exact test: allele P-value = 0.3432, genotype P-value = 0.0175 More... Significant association was found. Significant association was found. Positive
Ollila, H. M.,2009 C/T FBAT: P-value = 0.004187 FBAT: P-value = 0.004187 Significant association was observed Significant association was observed Positive
Baum, A. E., 2008 (a) C P-value = 0.001 when genotyped individually in the test samp...... P-value = 0.001 when genotyped individually in the test sample (NIMH); P-value = 0.004 when individually genotyped in the Replication sample (German); P-value = 0.000014 in the combined dataset. OR (95% CI)=1.67 (1.32-2.13) More... significant at the P < 0.05 level in both samples. significant at the P < 0.05 level in both samples. Trend

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
SORCS2 sortilin-related VPS10 domain containing receptor 2 4p16.1 5(3/2/0)

SNPs in LD with rs10937823 (count: 21) View in gBrowse (chr4:7470684..7490931 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 21)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)