BDgene

SNP Report

Basic Info
Name rs7683874 dbSNP Ensembl
Location chr4:7473697 - 7473697(1)
Variant Alleles G/A
Ancestral Allele G
Minor Allele A
Minor Allele Frequence 0.209065
Functional Annotation intron_variant; non_coding_transcript_variant.
Consequence to Transcript intron_variant(ENST00000329016, ENST00000507866, ENST00000511199); non_coding_transcript_variant(ENST00000511199)
No. of Studies 2 (Positive: 1; Negative: 1; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 2)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Ollila, H. M.,2009 G/A FBAT: P-value = 0.012695 FBAT: P-value = 0.012695 Significant association was observed Significant association was observed Positive
Baum, A. E., 2008 (a) G P-value = 0.041 when genotyped individually in the test samp...... P-value = 0.041 when genotyped individually in the test sample (NIMH); P-value = 0.006 when individually genotyped in the Replication sample (German); P-value = 0.0006 in the combined dataset. OR (95% CI)=1.51 (1.19-1.92) More... significant at the P < 0.05 level in both samples. significant at the P < 0.05 level in both samples. Negative

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
SORCS2 sortilin-related VPS10 domain containing receptor 2 4p16.1 5(3/2/0)

SNPs in LD with rs7683874 (count: 18) View in gBrowse (chr4:7473594..7490931 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 18)


Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback Acknowledgements
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Last update: March 31, 2016