GO Report

Basic Info
ID GO:0006954
Name inflammatory response
Type biological process
No. of Genes in BDgene  23
Source Pathway by PBA

PBA Result
Pathway Name in Paper Source Reference Data Set Tool Result Parameters Result Link
INFLAMMATORY RESPONSE i-GSEA analysis From NIMH STEP2 i-GSEA by using i-GSEA4GWAS P-value< 0.001, FDR=0.023 Link in i-GSEA4GWAS

GO related genes in BDgene (count: 23)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend) Evidence[PMID]
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 7p22 1(1/0/0) TAS[9572733]
CRHBP corticotropin releasing hormone binding protein 5q13.3 1(0/1/0) IDA[18559919]
IL6 interleukin 6 7p21-p15 1(0/1/0) IDA[10443688]
PRKCZ protein kinase C, zeta 1p36.33-p36.2 1(1/0/0) IEA
BDKRB1 bradykinin receptor B1 14q32.1-q32.2 1(1/0/0) IEA
TNF tumor necrosis factor 6p21.3 4(2/2/0) IDA[10748004]
NGF nerve growth factor (beta polypeptide) 1p13.1 2(1/1/0) IEA
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 7q22 1(0/0/1) TAS[17290298]
HDAC9 histone deacetylase 9 7p21.1 1(1/0/0) TAS[12711221]
IL10 interleukin 10 1q31-q32 1(0/1/0) IDA[10443688]
BDKRB2 bradykinin receptor B2 14q32.1-q32.2 1(1/0/0) IC[17077303]
AKT1 v-akt murine thymoma viral oncogene homolog 1 14q32.33 3(3/0/0) IEA
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 12q24 9(2/7/0) IEA
CCL2 chemokine (C-C motif) ligand 2 17q11.2-q21.1 3(1/2/0) IDA[21147091]
BMP6 bone morphogenetic protein 6 6p24-p23 1(1/0/0) IEA
ANXA1 annexin A1 9q21.13 1(0/0/1) TAS[10882119]
CRH corticotropin releasing hormone 8q13 2(1/1/0) IDA[18559919]
CNR2 cannabinoid receptor 2 (macrophage) 1p 1(1/0/0) IEA
TACR1 tachykinin receptor 1 2p13.1-p12 3(3/0/0) TAS[10854844]
ITGB6 integrin, beta 6 2q24.2 1(1/0/0) IEA
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 9q22.1 3(1/1/1) IEA
IL1B interleukin 1, beta 2q14 1(1/0/0) IDA[10748004]; NAS[1919436]
PROK2 prokineticin 2 3p21.1 1(0/1/0) NAS[11259612]