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GO Report
Basic Info
| ID | GO:0006954 |
|---|---|
| Name | inflammatory response |
| Type | biological process |
| No. of Genes in BDgene | 23 |
| Source | Pathway by PBA |
PBA Result
| Pathway Name in Paper | Source | Reference | Data Set | Tool | Result Parameters | Result Link |
|---|---|---|---|---|---|---|
| INFLAMMATORY RESPONSE | i-GSEA analysis | From NIMH | STEP2 | i-GSEA by using i-GSEA4GWAS | P-value< 0.001, FDR=0.023 | Link in i-GSEA4GWAS |
GO related genes in BDgene (count: 23)
| Approved Symbol | Approved Name | Location | No. of Studies (Positive/Negative/Trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| RAC1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 7p22 | 1(1/0/0) | TAS[9572733] |
| CRHBP | corticotropin releasing hormone binding protein | 5q13.3 | 1(0/1/0) | IDA[18559919] |
| IL6 | interleukin 6 | 7p21-p15 | 1(0/1/0) | IDA[10443688] |
| PRKCZ | protein kinase C, zeta | 1p36.33-p36.2 | 1(1/0/0) | IEA |
| BDKRB1 | bradykinin receptor B1 | 14q32.1-q32.2 | 1(1/0/0) | IEA |
| TNF | tumor necrosis factor | 6p21.3 | 4(2/2/0) | IDA[10748004] |
| NGF | nerve growth factor (beta polypeptide) | 1p13.1 | 2(1/1/0) | IEA |
| PIK3CG | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma | 7q22 | 1(0/0/1) | TAS[17290298] |
| HDAC9 | histone deacetylase 9 | 7p21.1 | 1(1/0/0) | TAS[12711221] |
| IL10 | interleukin 10 | 1q31-q32 | 1(0/1/0) | IDA[10443688] |
| BDKRB2 | bradykinin receptor B2 | 14q32.1-q32.2 | 1(1/0/0) | IC[17077303] |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 14q32.33 | 3(3/0/0) | IEA |
| P2RX7 | purinergic receptor P2X, ligand gated ion channel, 7 | 12q24 | 9(2/7/0) | IEA |
| CCL2 | chemokine (C-C motif) ligand 2 | 17q11.2-q21.1 | 3(1/2/0) | IDA[21147091] |
| BMP6 | bone morphogenetic protein 6 | 6p24-p23 | 1(1/0/0) | IEA |
| ANXA1 | annexin A1 | 9q21.13 | 1(0/0/1) | TAS[10882119] |
| CRH | corticotropin releasing hormone | 8q13 | 2(1/1/0) | IDA[18559919] |
| CNR2 | cannabinoid receptor 2 (macrophage) | 1p | 1(1/0/0) | IEA |
| TACR1 | tachykinin receptor 1 | 2p13.1-p12 | 3(3/0/0) | TAS[10854844] |
| ITGB6 | integrin, beta 6 | 2q24.2 | 1(1/0/0) | IEA |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 9q22.1 | 3(1/1/1) | IEA |
| IL1B | interleukin 1, beta | 2q14 | 1(1/0/0) | IDA[10748004]; NAS[1919436] |
| PROK2 | prokineticin 2 | 3p21.1 | 1(0/1/0) | NAS[11259612] |