BDgene

Region Report

Basic Info
Region Name 2q24
Chromosome Position chr2:154000000-168900000
No. of Studies (Positive/Negative/Trend)  4(0/3/1)

Region related studies (count: 4)
Reference Markers Statistical Values Author Comments Result Category
Service, S.,2006 rs964176 Two point parametric linkage analysis: LOD = 1.2767 Two point parametric linkage analysis: LOD = 1.2767 No significant linkage was found in this region. No significant linkage was found in this region. Negative
Nwulia, E. A.,2007 D2S1776, D2S1384 Non-parametric multipoint linkage analysis: For marker D2S17...... Non-parametric multipoint linkage analysis: For marker D2S1776, NPL = 1.67, P-value = 0.05; For marker D2S1384, NPL = 1.67, P-value = 0.05 More... No significant linkage was found in this region. No significant linkage was found in this region. Negative
Zandi, P. P.,2007 D2S1776 Linkage analyses: for narrow model, NPL(P-value) = 2.54(0.00...... Linkage analyses: for narrow model, NPL(P-value) = 2.54(0.005), LOD(P-value) = 1.99(0.0012); for broad model, NPL(P-value) = 2.04(0.02), LOD(P-value) = 1.32(0.007) More... Suggestive linkage was found in this region. Suggestive linkage was found in this region. Trend
Cassidy, F.,2007 D2S1353 Pairwise Linkage Analysis: Broad model, NPL = 1.66419, P-val...... Pairwise Linkage Analysis: Broad model, NPL = 1.66419, P-value = 0.048689 More... No significant linkage was found in this region. No significant linkage was found in this region. Negative

Region related genes (count: 10)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 2q24.3 1(1/0/0)
KCNH7 potassium channel, voltage gated eag related subfamily H, member 7 2q24.3 3(2/0/1)
PLA2R1 phospholipase A2 receptor 1, 180kDa 2q23-q24 1(1/0/0)
CCDC148 coiled-coil domain containing 148 2q24.1 1(0/1/0)
XIRP2 xin actin-binding repeat containing 2 2q31.1 1(0/1/0)
ITGB6 integrin, beta 6 2q24.2 1(1/0/0)
STK39 serine threonine kinase 39 2q24.3 2(0/2/0)
NR4A2 nuclear receptor subfamily 4, group A, member 2 2q22-q23 1(0/1/0)
SCN7A sodium channel, voltage gated, type VII alpha subunit 2q21-q23 1(0/1/0)
BAZ2B bromodomain adjacent to zinc finger domain, 2B 2q24.2 1(0/1/0)

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