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KEGG Pathway Report
Basic Info
| ID | hsa04350 |
|---|---|
| Name | TGF-beta signaling pathway |
| No. of Genes in BDgene | 10 |
| Source | Pathway by PBA |
PBA Result
| Pathway Name in Paper | Source | Reference | Data Set | Tool | Result Parameters | Result Link |
|---|---|---|---|---|---|---|
| TGF beta signaling pathway | PBA paper | Chang, S., 2015 | group A, group B | i-GSEA4GWAS v2, GenGen | FDR=0.1426 (A), 0.1456 (B) by i-GSEA4GWAS v2 |
Pathway related genes in BDgene (count: 10)
| Approved Symbol | Approved Name | Location | No. of Studies (Positive/Negative/Trend)  |
|---|---|---|---|
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 20q11 | 1(0/0/1) |
| CUL1 | cullin 1 | 7q36.1 | 1(1/0/0) |
| CREBBP | CREB binding protein | 16p13.3 | 1(0/1/0) |
| PPP2R2C | protein phosphatase 2, regulatory subunit B, gamma | 4p16.1 | 2(1/1/0) |
| IFNG | interferon, gamma | 12q14 | 2(2/0/0) |
| FST | follistatin | 5q11.2 | 1(0/0/1) |
| INHBB | inhibin, beta B | 2q14.2 | 1(0/1/0) |
| TNF | tumor necrosis factor | 6p21.3 | 4(2/2/0) |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 8p21.2 | 1(0/1/0) |
| BMP6 | bone morphogenetic protein 6 | 6p24-p23 | 1(1/0/0) |