SNP Report

Basic Info

Name	rs2287161 dbSNP Ensembl
Location	chr12:106987362 - 106987362(1)
Variant Alleles	C/G
Ancestral Allele	C
Minor Allele	C
Minor Allele Frequence	0.463858
Functional Annotation	downstream_gene_variant; upstream_gene_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000008527, ENST00000552790); upstream_gene_variant(ENST00000240050, ENST00000392830, ENST00000547115, ENST00000548101, ENST00000550496, ENST00000550736, ENST00000552029)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	YES

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Soria, V.,2010			X²-tests: allele P-value = 0.036, Model Log-addit...... X²-tests: allele P-value = 0.036, Model Log-additive, genotype P-value = 0.043, OR(95%CI)=0.78 (0.62-0.99) More...	Significant association was found in BD. Significant association was found in BD.	Positive

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
CRY1	cryptochrome circadian clock 1	12q23-q24.1	2(1/1/0)
MTERFD3	mitochondrial transcription termination factor 2	12q24.1	Mapped by Literature SNP

SNPs in LD with rs2287161 (count: 0) View in gBrowse (chr12:106987362..106987362 )

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 1)

Reference	Statistical Result	Description	Result Category
Soria, V.,2010	X²-tests:allele P-value > 0.05, genotype P-value > 0.05 in all model	No significant association was observed.	Negative