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KEGG Pathway Report
Basic Info
| ID | hsa04620 |
|---|---|
| Name | Toll-like receptor signaling pathway |
| No. of Genes in BDgene | 10 |
| Source | Pathway by Database Search |
Pathway related genes in BDgene (count: 10)
| Approved Symbol | Approved Name | Location | No. of Studies (Positive/Negative/Trend)  |
|---|---|---|---|
| MAP2K6 | mitogen-activated protein kinase kinase 6 | 17q | 1(0/1/0) |
| IL1B | interleukin 1, beta | 2q14 | 1(1/0/0) |
| MAPK10 | mitogen-activated protein kinase 10 | 4q22-q23 | 1(0/1/0) |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 5q13.1 | 1(1/0/0) |
| IL6 | interleukin 6 | 7p21-p15 | 1(0/1/0) |
| RAC1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 7p22 | 1(1/0/0) |
| PIK3CG | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma | 7q22 | 1(0/0/1) |
| TNF | tumor necrosis factor | 6p21.3 | 4(2/2/0) |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 14q32.33 | 3(3/0/0) |
| TLR4 | toll-like receptor 4 | 9q33.1 | 1(1/0/0) |