BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

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Region Report

Basic Info

Region Name	22q13.1
Chromosome Position	chr22:37200000-40600000
No. of Studies (Positive/Negative/Trend)	1(0/0/1)

Region related studies (count: 1)

Reference	Markers	Statistical Values	Author Comments	Result Category
Nievergelt, C. M., 2006	D22S283, D22S423	LOD = 0.07 for marker D22S283 at Theta = 0 for the narrow d...... LOD = 0.07 for marker D22S283 at Theta = 0 for the narrow diagnostic and AD50 genetic model; LOD = 1.92 at Theta = 0.05 for the narrow diagnostic and AD50 genetic model; LOD = 2.22 at Theta = 0.1 for the narrow diagnostic and AD50 genetic model; LOD = -8.16 for marker D22S423 at Theta = 0 for the broad diagnostic and AR50 genetic model; LOD = -3.28 at Theta = 0.05 for the broad diagnostic and AD50 genetic model; LOD = -1.62 at Theta = 0.1 for the broad diagnostic and AD50 genetic model More...	With the exception of D22S283, no positive LOD scores were o...... With the exception of D22S283, no positive LOD scores were obtained under any of the six models for the overall marker versus disease analysis. A maximum LOD of 2.22, which is suggestive for linkage, was obtained for D22S283 at Theta=0.1 for the narrow diagnostic and AD50 genetic model. More...	Trend

Region related genes (count: 9)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
PICK1	protein interacting with PRKCA 1	22q13.1	1(0/1/0)
PLA2G6	phospholipase A2, group VI (cytosolic, calcium-independent)	22q13.1	2(1/1/0)
CSNK1E	casein kinase 1, epsilon	22q13.1	5(1/3/1)
ATF4	activating transcription factor 4	22q13.1	1(1/0/0)
SYNGR1	synaptogyrin 1	22q13	3(2/1/0)
FAM83F	family with sequence similarity 83, member F	22q13.1	1(0/1/0)
CYTH4	cytohesin 4	22q12.3-q13.1	1(1/0/0)
TNRC6B	trinucleotide repeat containing 6B	22q13	1(1/0/0)
ADSL	adenylosuccinate lyase	22q13.1	2(1/1/0)

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Region: chr22:37200000..40600000 View in gBrowse