Search SNP
Search Gene
Search CNV
Search Haplotype
Search Other Variant
Search Region
Search Pathway
Search Study
GO Report
Basic Info
| ID | GO:0005262 |
|---|---|
| Name | calcium channel activity |
| Type | molecular function |
| No. of Genes in BDgene | 9 |
| Source | Pathway by PBA |
PBA Result
| Pathway Name in Paper | Source | Reference | Data Set | Tool | Result Parameters | Result Link |
|---|---|---|---|---|---|---|
| GO: 0005262: Ca2+ channel act. | PBA paper | Askland, K.,2009 | WTCCC Bayesian genotypic | Fisher's exact test | P < 0.05 from the WTCCC PBAs | |
| CALCIUM CHANNEL ACTIVITY | i-GSEA analysis | From NIMH | Trinity College Dublin | i-GSEA by using i-GSEA4GWAS | P-value< 0.001, FDR=0.033 | Link in i-GSEA4GWAS |
| GO: 0005262: Ca2+ channel act. | PBA paper | Askland, K.,2009 | NIMH | Fisher's exact test | Results given for gene sets with P < 0.05 from the NIMH PBA; Molecular function | |
| GO: 0005262: Ca2+ channel act. | PBA paper | Askland, K.,2009 | WTCCC Frequentist genotypic | Fisher's exact test | P < 0.05 from the WTCCC PBAs |
GO related genes in BDgene (count: 9)
| Approved Symbol | Approved Name | Location | No. of Studies (Positive/Negative/Trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | 10p12 | 3(2/1/0) | NAS[9594024] |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 12p13.1 | 8(4/4/0) | IEA |
| CHRNA9 | cholinergic receptor, nicotinic, alpha 9 (neuronal) | 4p14 | 2(0/2/0) | IEA |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 | 21q22.3 | 5(3/2/0) | IEA |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 16p13.2 | 1(1/0/0) | IEA |
| GRIN3A | glutamate receptor, ionotropic, N-methyl-D-aspartate 3A | 9q31.1 | 1(0/1/0) | IEA |
| CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) | 11p15.5 | 1(0/1/0) | IEA |
| RYR2 | ryanodine receptor 2 (cardiac) | 1q43 | 1(1/0/0) | ISS |
| GRIN1 | glutamate receptor, ionotropic, N-methyl D-aspartate 1 | 9q34.3 | 3(2/1/0) | IDA[7685113] |