BDgene

Gene Report

Basic Info
Approved Symbol IRF8
Previous Symbol ICSBP1
Symbol Alias IRF-8, ICSBP
Approved Name interferon regulatory factor 8
Previous Name interferon consensus sequence binding protein 1
Location 16q24.1
Position chr16:85898803-85922609, 1
External Links HGNC: 5358
Entrez Gene: 3394
Ensembl: ENSG00000140968
UCSC: uc002fjh.3
No. of Studies 1 (Positive: 1; Negative: 0; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 1)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Hattori, E.,2009 SNP: rs10514611 After the two-stage analysis, markers in this gene remained nominally significant (allelic P<0.05) with the same allele being consistently over-represented in both the first and the follow-up stages. Positive Comment on Study
Gene functional annotation
Gene related GO terms (count: 20)

GO terms by PBA (count: 0)

GO terms by database search (count: 20)


Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 6)

Related other genetic factors
Gene related SNPs (count: 4)

Literature-origin SNPs (count: 1)

LD-proxies (count: 3)


Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 2)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

View in gBrowse

Region: chr16:85898803..85922609 View in gBrowse
View in gBrowse