SNP Report

Basic Info

Name	rs3775552 dbSNP Ensembl
Location	chr4:184403033 - 184403033(1)
Variant Alleles	C/A
Ancestral Allele	C
Minor Allele	A
Minor Allele Frequence	0.205671
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000393593, ENST00000502750, ENST00000505067)
No. of Studies	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Hattori, E.,2009			In GWAS: Allelic P-value = 0.07861, Genotypic P-value = 0.00...... In GWAS: Allelic P-value = 0.07861, Genotypic P-value = 0.00984, Recessive P-value = 0.00327, HWE P-value = 0.03751; in Follow-up study: MAF=0.38, Allelic P-value = 0.03749, Allelic Q-value=0.55728, HWE P-value = 0.63561 More...	Significant association was observed in both GWAS and Follow...... Significant association was observed in both GWAS and Follow-up study. More...	Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
IRF2	interferon regulatory factor 2	4q34.1-q35.1	1(1/0/0)

SNPs in LD with rs3775552 (count: 2) View in gBrowse (chr4:184402572..184403456 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs724528		intron_variant	1.0[CHB]; 0.91[CHD]; 0.948[JPT]
rs809909		downstream_gene_variant; intron_variant	0.815[CHB]; 0.815[CHD]; 0.812[JPT]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)