BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

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Region Report

Basic Info

Region Name	4q35
Chromosome Position	chr4:182300000-190214555
No. of Studies (Positive/Negative/Trend)	4(0/1/3)

Region related studies (count: 4)

Reference	Markers	Statistical Values	Author Comments	Result Category
Badenhop, R. F.,2003	D4S1540, D4S3051, D4S426, D4S1652	Linkage Analysis: For marker D4S1540, LOD = 1.57, Model 60%r...... Linkage Analysis: For marker D4S1540, LOD = 1.57, Model 60%recessive, P-value = 0.0009; For marker D4S3051, LOD = 2.32, Model 60% recessive, P-value = 0.0001; D4S426, LOD = 2.49, Model 60%dominant, P-value = 0.0007; For marker D4S1652, LOD = 3.19, Model 90%dominant, P-value = 0.0005 More...	Suggestive linkage was found in this region. Suggestive linkage was found in this region.	Trend
McInnis, M. G.,2003(a)	D4S2390	Linkage analysis: model III, Unconditional NPL = 1 Linkage analysis: model III, Unconditional NPL = 1	No significant linkage was found in this region. No significant linkage was found in this region.	Negative
Willour, V. L.,2003	D4S3335, D4S2390	liknage analysis: LOD = 2.49 liknage analysis: LOD = 2.49	Suggestive linkage was found in this region. Suggestive linkage was found in this region.	Trend
McInnis, M. G.,2003(b)	D4S3051	Linkage analysis: Model BPUP, NPL = 2.43, P-value = 0.01, LO...... Linkage analysis: Model BPUP, NPL = 2.43, P-value = 0.01, LOD(ASM) = 1.2 More...	Suggestive linkage was found in this region. Suggestive linkage was found in this region.	Trend

Region related genes (count: 7)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
FAM149A	family with sequence similarity 149, member A	4q35.1	1(0/1/0)
MTNR1A	melatonin receptor 1A	4q35	1(0/1/0)
LRP2BP	LRP2 binding protein	4q35.1	1(0/1/0)
TRIML2	tripartite motif family-like 2	4q35.2	1(0/1/0)
KIAA1430	cilia and flagella associated protein 97	4q35.1	0
IRF2	interferon regulatory factor 2	4q34.1-q35.1	1(1/0/0)
CFAP97	cilia and flagella associated protein 97	4q35.1	1(0/1/0)

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Region: chr4:182300000..190214555 View in gBrowse