Gene Report

Basic Info
Approved Symbol FBN1
Previous Symbol FBN, MFS1, WMS
Symbol Alias MASS, OCTD, SGS
Approved Name fibrillin 1
Previous Name fibrillin 1 (Marfan syndrome)
Name Alias Marfan syndrome
Location 15q21.1
Position chr15:48408306-48645849, -1
External Links HGNC: 3603
Entrez Gene: 2200
Ensembl: ENSG00000166147
UCSC: uc001zwx.2
No. of Studies 2 (Positive: 0; Negative: 2; trend: 0)
Overlap with SZ? NO
Overlap with MDD? NO
Gene related studies (count: 2)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Djurovic, S.,2010 SNP: rs1566816, rs1848053, rs8042197, rs931781 No significant association of this gene was observed in BD. Negative Comment on Study
Xu, W., 2014 SNP: rs16961283 The SNP within or near this gene did not achieve genome-wide significance. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 18)

GO terms by PBA (count: 2)

GO terms by database search (count: 16)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 10)

Related other genetic factors
Gene related SNPs (count: 16)

Literature-origin SNPs (count: 5)

LD-proxies (count: 11)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Gene relationship with MDD

View in gBrowse

Region: chr15:48408306..48645849 View in gBrowse
View in gBrowse