Study Report

Basic Info
Citation Cichon, S., I. Winge, et al. (2008). "Brain-specific tryptophan hydroxylase 2 (TPH2): a functional Pro206Ser substitution and variation in the 5'-region are associated with bipolar affective disorder." Hum Mol Genet 17(1): 87-97.
Disease Type Bipolar I Disorder
Study Design case-control
Study Type Candidate-gene association study
Sample Size The sample comprised 636 BPAD patients and 1070 population-based controls of German descen.
SNP/Region/Marker Size 15 SNPs
Predominant Ethnicity Caucasian
Population Germany and Russia
Gender 47% male and 53% female for the German cases; 51.5% female and 48.5% male for the German control sample. 44.1% male and 55.9% female for the Russian cases; 54.3% female and 45.7% male for the Russian control sample.
Age Group adults : The German patients: mean age=43.7 (SD=13.1) years; the German controls: mean age=48.4 (SD=15.5) years. The Russian patients: mean age of oneset=26.8 (SD=11.3) years; the Russian controls: mean age=38.1 (SD=15.4) years.

Detail Info

SNPs reported by this study for BD (count: 15)

Genes reported by this study for BD (count: 1)