SNP Report

Basic Info

Name	rs11178999 dbSNP Ensembl
Location	chr12:71939790 - 71939790(1)
Variant Alleles	G/A
Ancestral Allele	A
Minor Allele	A
Minor Allele Frequence	0.347444
Functional Annotation	intron_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000333850, ENST00000546576); non_coding_transcript_variant(ENST00000546576)
No. of Studies	2 (Positive: 1; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Grigoroiu-Serbanescu, M.,2008	G/A		Cochrane-Armitage trend test P value=0.172 Cochrane-Armitage trend test P value=0.172		Negative
Cichon, S., 2008	G/A	A	Cochrane-Armitage trend test P-value > .0.5 in the German BP...... Cochrane-Armitage trend test P-value > .0.5 in the German BPAD sample. Cochrane-Armitage trend test P-value = 0.34 in the Russian BPAD sample. Cochrane-Armitage trend test P-value = 0.29 in Combined German/Russian sample. More...		Positive

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
TPH2	tryptophan hydroxylase 2	12q15	13(10/3/0)

SNPs in LD with rs11178999 (count: 1) View in gBrowse (chr12:71936332..71939790 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs6582071		upstream_gene_variant	0.861[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)