BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

Search Gene with Disease Search Gene1 with Disease

Region Report

Basic Info

Region Name	10q21
Chromosome Position	chr10:51100000-68800000
No. of Studies (Positive/Negative/Trend)	4(0/3/1)

Region related studies (count: 4)

Reference	Markers	Statistical Values	Author Comments	Result Category
Liu, J.,2003	D10S1225	Two-point parametric linkage results: Maximum LOD = 1.99, Mo...... Two-point parametric linkage results: Maximum LOD = 1.99, Model BP2, Dominant, theta = 0.2 More...	Suggestive linkage was found in this region. Suggestive linkage was found in this region.	Trend
Xu, H.,2010	D10S1225	linkage study: for BP2, Dominant model, LOD = 0 in new pedig...... linkage study: for BP2, Dominant model, LOD = 0 in new pedigrees(N = 16); LOD = 0.24 in all pedigrees(N = 56) More...	No significant linkage was found in this region. No significant linkage was found in this region.	Negative
Xu, H.,2011	D10S1225	Linkage study: for BP2, Dominant model, LOD = 0 for New pedi...... Linkage study: for BP2, Dominant model, LOD = 0 for New pedigrees(N = 16), LOD = 0.24 for all pedigrees(N = 56); More...	No significant linkage was found in this region. No significant linkage was found in this region.	Negative
Service, S.,2006	rs284604	Two point parametric linkage analysis: LOD = 1.2033 Two point parametric linkage analysis: LOD = 1.2033	No significant linkage was found in this region. No significant linkage was found in this region.	Negative

Region related genes (count: 7)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
CTNNA3	catenin (cadherin-associated protein), alpha 3	10q21	1(1/0/0)
PCDH15	protocadherin-related 15	10q21.1	4(2/1/1)
SIRT1	sirtuin 1	10q21	1(0/1/0)
EGR2	early growth response 2	10q21.1	3(1/2/0)
TFAM	transcription factor A, mitochondrial	10q21	1(1/0/0)
ANK3	ankyrin 3, node of Ranvier (ankyrin G)	10q21	17(13/3/1)
ZWINT	ZW10 interacting kinetochore protein	10q21-q22	1(1/0/0)

View in gBrowse

Region: chr10:51100000..68800000 View in gBrowse