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KEGG Pathway Report
Basic Info
| ID | hsa00590 |
|---|---|
| Name | Arachidonic acid metabolism |
| No. of Genes in BDgene | 7 |
| Source | Pathway by PBA |
PBA Result
| Pathway Name in Paper | Source | Reference | Data Set | Tool | Result Parameters | Result Link |
|---|---|---|---|---|---|---|
| Arachidonic acid metabolism | PBA paper | Chen, L., 2009 | WTCCC | Prioritizing Risk Pathways fusing SNPs and pathways (PRP) | risk score=0.73 |
Pathway related genes in BDgene (count: 7)
| Approved Symbol | Approved Name | Location | No. of Studies (Positive/Negative/Trend)  |
|---|---|---|---|
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) | 22q13.1 | 2(1/1/0) |
| ALOX12 | arachidonate 12-lipoxygenase | 17p13.1 | 2(1/1/0) |
| TBXAS1 | thromboxane A synthase 1 (platelet) | 7q34-q35 | 1(0/1/0) |
| CBR3 | carbonyl reductase 3 | 21q22.2 | 1(0/0/1) |
| GPX6 | glutathione peroxidase 6 | 6p22.1 | 1(1/0/0) |
| GPX3 | glutathione peroxidase 3 | 5q33.1 | 1(1/0/0) |
| PLA2G1B | phospholipase A2, group IB (pancreas) | 12q24.31 | 4(1/3/0) |