Gene Report

Basic Info
Approved Symbol NALCN
Previous Symbol VGCNL1
Symbol Alias bA430M15.1, CanIon
Approved Name sodium leak channel, non selective
Previous Name voltage gated channel like 1, "sodium leak channel, non-selective"
Location 13q32.3
Position chr13:101053776-101416492, -1
External Links HGNC: 19082
Entrez Gene: 259232
Ensembl: ENSG00000102452
UCSC: uc001vox.1
No. of Studies 2 (Positive: 0; Negative: 2; trend: 0)
Overlap with SZ? YES
Overlap with MDD? NO
Gene related studies (count: 2)
Reference Tested Markers Statistical Values/Author Comments Result Category Comment on Study
Ollila, H. M.,2009 SNP: rs9513877 It showed no evidence for association with BPI in our study. Negative Comment on Study
Xu, W., 2014 SNP: rs10508054 The SNP within or near this gene did not achieve genome-wide significance. Negative Comment on Study
Gene functional annotation
Gene related GO terms (count: 13)

GO terms by PBA (count: 3)

GO terms by database search (count: 10)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors
Gene related SNPs (count: 45)

Literature-origin SNPs (count: 3)

LD-proxies (count: 42)

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)
Gene relationship with SZ

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with SZ from candidate gene intersection analysis (count: 1)

Gene relationship with MDD

View in gBrowse

Region: chr13:101053776..101416492 View in gBrowse
View in gBrowse