SNP Report

Basic Info

Name	rs10508054 dbSNP Ensembl
Location	chr13:101140108 - 101140108(1)
Variant Alleles	A/C
Ancestral Allele	A
Minor Allele	C
Minor Allele Frequence	0.152955
Functional Annotation	downstream_gene_variant; intron_variant; non_coding_transcript_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000497170); intron_variant(ENST00000251127, ENST00000467264); non_coding_transcript_variant(ENST00000467264)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Xu, W., 2014	C/A		Adjusted P (ADD)=2.12E-03ï¼ŒÂ OR=0.7002 Adjusted P (ADD)=2.12E-03ï¼ŒÂ OR=0.7002	SNPs from top 1000 from our combined CAMH/IoP GWAS for BPAD,...... SNPs from top 1000 from our combined CAMH/IoP GWAS for BPAD, for which at least one other non-overlapping GWAS also shows association at same gene. More...	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
NALCN	sodium leak channel, non selective	13q32.3	2(0/2/0)

SNPs in LD with rs10508054 (count: 4) View in gBrowse (chr13:101123958..101140108 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs667973	intron_variant; non_coding_transcript_variant	0.815[CEU]
rs646169	intron_variant; non_coding_transcript_variant	0.815[CEU]
rs17621541	downstream_gene_variant; intron_variant; non_coding_transcript_variant	1.0[CEU]
rs17677956	intron_variant; non_coding_transcript_variant	1.0[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)