BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

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GO Report

Basic Info

ID	GO:0005245
Name	voltage-gated calcium channel activity
Type	molecular function
No. of Genes in BDgene	14
Source	Pathway by PBA

PBA Result

Pathway Name in Paper	Source	Reference	Data Set	Tool	Result Parameters	Result Link
GO: 0005245: voltage-gated Ca2+ channel act.	PBA paper	Askland, K.,2009	NIMH	Fisher's exact test	Results given for gene sets with P < 0.05 from the NIMH PBA; Molecular function

GO related genes in BDgene (count: 14)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)	Evidence[PMID]
CACNA2D4	calcium channel, voltage-dependent, alpha 2/delta subunit 4	12p13.33	1(1/0/0)	IDA[12181424]
CACNG2	calcium channel, voltage-dependent, gamma subunit 2	22q13.1	3(3/0/0)	IEA
CACNG5	calcium channel, voltage-dependent, gamma subunit 5	17q24	2(1/1/0)	TAS[10613843]
CACNB2	calcium channel, voltage-dependent, beta 2 subunit	10p12	3(2/1/0)	IDA[1309651]
CACNA2D1	calcium channel, voltage-dependent, alpha 2/delta subunit 1	7q21-q22	2(0/0/2)	IDA[1309651]; IDA[11160515]
CACNG1	calcium channel, voltage-dependent, gamma subunit 1	17q24	1(0/1/0)	IEA
CACNA1C	calcium channel, voltage-dependent, L type, alpha 1C subunit	12p13.3	20(17/3/0)	IDA[12130699]
CACNA1S	calcium channel, voltage-dependent, L type, alpha 1S subunit	1q32	1(0/1/0)	IDA[9852570]
NALCN	sodium leak channel, non selective	13q32.3	2(0/2/0)	IBA
CACNB3	calcium channel, voltage-dependent, beta 3 subunit	12q13	1(0/0/1)	IDA[11160515]
CACNA1E	calcium channel, voltage-dependent, R type, alpha 1E subunit	1q25.3	1(1/0/0)	IDA[8071363]
CACNA1D	calcium channel, voltage-dependent, L type, alpha 1D subunit	3p14.3	1(1/0/0)	IDA[11160515]
GRM7	glutamate receptor, metabotropic 7	3p26-p25	3(2/1/0)	IEA
CACNA1B	calcium channel, voltage-dependent, N type, alpha 1B subunit	9q34	1(1/0/0)	TAS[1321501]