SNP Report

Basic Info

Name	rs11869073 dbSNP Ensembl
Location	chr17:69480672 - 69480672(1)
Variant Alleles	A/C
Ancestral Allele	A
Minor Allele	C
Minor Allele Frequence	0.0948482
Functional Annotation	intron_variant; NMD_transcript_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000359094, ENST00000585537, ENST00000586641, ENST00000590474); NMD_transcript_variant(ENST00000359094); non_coding_transcript_variant(ENST00000585537, ENST00000586641)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Xu, W., 2014	C/A		P(unadj)-value=5.45E-05,Â OR (unadj)=0.7057,Â P(adj)-value=2...... P(unadj)-value=5.45E-05,Â OR (unadj)=0.7057,Â P(adj)-value=2.52E-05,Â OR (adj)=0.6911 More...	Top 68 SNPs (showing suggestive association to BD: p<0.0001)...... Top 68 SNPs (showing suggestive association to BD: p<0.0001) in our combined (CAMH and IoP) GWAS. More...	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
MAP2K6	mitogen-activated protein kinase kinase 6	17q	1(0/1/0)

SNPs in LD with rs11869073 (count: 1) View in gBrowse (chr17:69473307..69480672 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Functional Annotation	r²[population]
rs12945375		downstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant	0.943[CEU]; 0.957[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)