BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

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Region Report

Basic Info

Region Name	9q21
Chromosome Position	chr9:65000000-87800000
No. of Studies (Positive/Negative/Trend)	3(1/1/1)

Region related studies (count: 3)

Reference	Markers	Statistical Values	Author Comments	Result Category
McInnis, M. G.,2003(a)	D9S1119	Linkage analysis: model I, Unconditional NPL = 1.4 Linkage analysis: model I, Unconditional NPL = 1.4	No significant linkage was found in this region. No significant linkage was found in this region.	Negative
Cassidy, F.,2007	D9S301	Pairwise Linkage Analysis: Broad model, NPL = 2.17142, P-val...... Pairwise Linkage Analysis: Broad model, NPL = 2.17142, P-value = 0.015383; narrow model, NPL = 1.62595, P-value = 0.053312; Structure-Guided Linkage Analysis: Broad model: NPL = 2.16, P-value = 0.016 for all families.; NPL = 1.68, P-value = 0.045 for families.; Narrow model: NPL = 1.62, P-value = 0.054 for all families.; NPL = 1.8, P_value = 0.037 for 60% homogeneous families. More...	There is a trend for Significant linkage. There is a trend for Significant linkage.	Trend
Badner, J. A.,2012	rs722642	Merlin analysis: affection status model 1: Pairs-LOD = 3.4 Merlin analysis: affection status model 1: Pairs-LOD = 3.4	Significant linkage was found in this region. Significant linkage was found in this region.	Positive

Region related genes (count: 6)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
RORB	RAR-related orphan receptor B	9q22	4(3/1/0)
PCSK5	proprotein convertase subtilisin/kexin type 5	9q21.13	1(1/0/0)
ANXA1	annexin A1	9q21.13	1(0/0/1)
TLE4	transducin-like enhancer of split 4	9q21.32	2(1/1/0)
FRMD3	FERM domain containing 3	9q21.33	1(0/1/0)
NTRK2	neurotrophic tyrosine kinase, receptor, type 2	9q22.1	3(1/1/1)

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Region: chr9:65000000..87800000 View in gBrowse