Gene Report

ADD to My Gene Set

Basic Info

Approved Symbol	FAM149A
Symbol Alias	DKFZP564J102, MST119, MSTP119
Approved Name	family with sequence similarity 149, member A
Location	4q35.1
Position	chr4:186104419-186172667, 1
External Links	HGNC: 24527 Entrez Gene: 25854 Ensembl: ENSG00000109794 UCSC: uc010isl.3
No. of Studies	1 (Positive: 0; Negative: 1; trend: 0)
Overlap with SZ?	NO
Overlap with MDD?	NO

Gene related studies (count: 1)

Reference	Tested Markers	Statistical Values/Author Comments	Result Category	Comment on Study
Blair, I. P.,2005	SNP: rs17880686, rs17881021, rs17881380, rs17882808, rs17884524, rs17886141, rs2276913, rs2276914	Our data suggest that this candidate gene analyzed can be excluded from involvement in the disorder.	Negative	Comment on Study

Gene functional annotation

Gene related GO terms (count: 0)

Gene related KEGG pathways (count: 0)

Gene related BioCarta pathways (count: 0)

Gene related interactors from protein-protein interactions data in HPRD (count: 0)

Related other genetic factors

Gene related SNPs (count: 15)

rs_ID	Location	Functional Annotation	No. of Studies (Positive/Negative/Trend)
rs17881380	chr4:186156000 - 186156000(1)	downstream_gene_variant; missense_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; splice_region_variant; upstream_gene_variant	1(0/1/0)
rs17886141	chr4:186156012 - 186156012(1)	downstream_gene_variant; missense_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; upstream_gene_variant	1(0/1/0)
rs17884524	chr4:186156024 - 186156024(1)	downstream_gene_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; synonymous_variant; upstream_gene_variant	1(0/1/0)
rs2276914	chr4:186151778 - 186151778(1)	downstream_gene_variant; intron_variant; non_coding_transcript_variant	1(0/1/0)
rs17881021	chr4:186156015 - 186156015(1)	downstream_gene_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; synonymous_variant; upstream_gene_variant	1(0/1/0)
rs17880686	chr4:186155978 - 186155978(1)	downstream_gene_variant; intron_variant; non_coding_transcript_variant; upstream_gene_variant	1(0/1/0)
rs17882808	chr4:186149783 - 186149783(1)	downstream_gene_variant; intron_variant; non_coding_transcript_variant	1(0/1/0)
rs2276913	chr4:186151846 - 186151846(1)	downstream_gene_variant; intron_variant; non_coding_transcript_variant	1(0/1/0)

rs_ID	Location	Functional Annotation
rs7668227	chr4:186139930 - 186139930(1)	intron_variant; non_coding_transcript_variant; upstream_gene_variant
rs6858112	chr4:186141272 - 186141272(1)	intron_variant; non_coding_transcript_variant; upstream_gene_variant
rs13141920	chr4:186143399 - 186143399(1)	intron_variant; non_coding_transcript_variant; upstream_gene_variant
rs2276912	chr4:186151876 - 186151876(1)	downstream_gene_variant; intron_variant; non_coding_transcript_variant
rs7684126	chr4:186151229 - 186151229(1)	downstream_gene_variant; intron_variant; non_coding_transcript_variant
rs4862653	chr4:186156052 - 186156052(1)	downstream_gene_variant; missense_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; upstream_gene_variant
rs4862650	chr4:186153679 - 186153679(1)	downstream_gene_variant; missense_variant; non_coding_transcript_exon_variant; non_coding_transcript_variant; upstream_gene_variant

Gene related CNVs (count: 0)

Gene related other variants (count: 0)

Gene related regions (count: 3)

Region Name	Position	No. of Studies (Positive/Negative/Trend)
Chr 4	chr4:0-190214555	3 (0/3/0)
4q35	chr4:182300000-190214555	4 (0/1/3)
4q31-35	chr4:138500000-190214555	1 (0/1/0)

Overlap with schizophrenia (SZ) and major depressive disorder (MDD)

Gene relationship with SZ

Gene relationship with MDD

View in gBrowse

Region: chr4:186104419..186172667 View in gBrowse