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KEGG Pathway Report
Basic Info
| ID | hsa05222 |
|---|---|
| Name | Small cell lung cancer |
| No. of Genes in BDgene | 8 |
| Source | Pathway by PBA |
PBA Result
| Pathway Name in Paper | Source | Reference | Data Set | Tool | Result Parameters | Result Link |
|---|---|---|---|---|---|---|
| Small cell lung cancer | PBA paper | Peng, G., 2010 | WTCCC | hypergeometric test (Fisher's exact test), Sidak's method, Simes' method, Simes/FDR method | Fisher exact test P-value=0.0102103 |
Pathway related genes in BDgene (count: 8)
| Approved Symbol | Approved Name | Location | No. of Studies (Positive/Negative/Trend)  |
|---|---|---|---|
| NOS1 | nitric oxide synthase 1 (neuronal) | 12q24.22 | 8(2/5/1) |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 5q13.1 | 1(1/0/0) |
| BCL2 | B-cell CLL/lymphoma 2 | 18q21.3 | 2(0/2/0) |
| LAMA3 | laminin, alpha 3 | 18q11.2 | 1(0/0/1) |
| LAMB1 | laminin, beta 1 | 7q22 | 1(0/0/1) |
| NOS3 | nitric oxide synthase 3 (endothelial cell) | 7q36 | 2(1/1/0) |
| PIK3CG | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma | 7q22 | 1(0/0/1) |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 14q32.33 | 3(3/0/0) |