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KEGG Pathway Report
Basic Info
| ID | hsa01030 |
|---|---|
| Name | Glycan structures - biosynthesis 1 |
| No. of Genes in BDgene | 8 |
| Source | Pathway by PBA |
PBA Result
| Pathway Name in Paper | Source | Reference | Data Set | Tool | Result Parameters | Result Link |
|---|---|---|---|---|---|---|
| Glycan structures biosynthesis 1 | PBA paper | Peng, G., 2010 | WTCCC | hypergeometric test (Fisher's exact test), Sidak's method, Simes' method, Simes/FDR method | Fisher exact test P-value=0.000266725; Simes/FDR P-value<1E-20 | |
| Glycan structures biosynthesis 1 | PBA paper | O'Dushlaine, C.,2011 | WTCCC | SNP ratio test | P-value=0.001 |
Pathway related genes in BDgene (count: 8)
| Approved Symbol | Approved Name | Location | No. of Studies (Positive/Negative/Trend)  |
|---|---|---|---|
| HS6ST2 | heparan sulfate 6-O-sulfotransferase 2 | Xq26.2 | 1(0/0/1) |
| NDST3 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 | 4q26 | 1(1/0/0) |
| MGAT4A | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A | 2q12 | 1(0/0/1) |
| EXTL1 | exostosin-like glycosyltransferase 1 | 1p36.1 | 1(1/0/0) |
| ALG9 | ALG9, alpha-1,2-mannosyltransferase | 11q23 | 1(0/1/0) |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 8q24.22 | 4(3/0/1) |
| GALNT13 | polypeptide N-acetylgalactosaminyltransferase 13 | 2q24.1 | 1(0/1/0) |
| ALG10B | ALG10B, alpha-1,2-glucosyltransferase | 12q12 | 1(0/1/0) |