SNP Report

Basic Info
Name rs7565062 dbSNP Ensembl
Location chr2:166477575 - 166477575(1)
Variant Alleles G/T
Ancestral Allele T
Minor Allele G
Minor Allele Frequence 0.311302
Functional Annotation missense_variant; NMD_transcript_variant.
Polyphen Annotation: benign(ENST00000409855, ENST00000419992, ENST00000424326, ENST00000619410, ENST00000621965, ENST00000441411)
SIFT Annotation: tolerated - low confidence(ENST00000441411); tolerated(ENST00000409855, ENST00000419992, ENST00000424326, ENST00000619410, ENST00000621965)
Consequence to Transcript missense_variant(ENST00000409855, ENST00000419992, ENST00000424326, ENST00000619410, ENST00000621965, ENST00000441411); NMD_transcript_variant(ENST00000424326)
No. of Studies 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature
Overlap with SZ? NO
Overlap with MDD? NO

SNP related studies (count: 1)
Reference Allele Change Risk Allele Statistical Values Author Comments Result Category
Xu, W., 2014 P(unadj)-value=0.000654, OR (unadj)=0.782, P(adj)-value=0....... P(unadj)-value=0.000654, OR (unadj)=0.782, P(adj)-value=0.001399, OR(adj)=0.7927 More... Listing suggestive significant genic SNPs for combined Toron...... Listing suggestive significant genic SNPs for combined Toronto and London GWAS for which there are 4 or more suggestive significant SNPs among the top 1000, and for which no other positive reports have been published to date. More... Negative

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Studies (Positive/Negative/Trend)
SCN7A sodium channel, voltage gated, type VII alpha subunit 2q21-q23 1(0/1/0)

SNPs in LD with rs7565062 (count: 9) View in gBrowse (chr2:166425242..166502173 )
The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 9)

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)