SNP |
Related Gene(s) |
Allele Change |
Risk Allele |
Statistical Values |
Author Comments |
Result Category |
rs10776799 |
NGF
|
G/T |
|
Primary GWAS P-value(GC)=0.0000484, OR=1.15; replication P-value(1-sided)=0.434, OR=1.01; Combined GWAS and replication P-value(GC)=0.00125, OR=1.08
|
No significant association was observed.
No significant association was observed.
|
Negative
|
rs10028075 |
MAPK10
|
C/T |
|
Primary GWAS P-value(GC)=0.00000896, OR=0.89; replication P-value(1-sided)=1, OR=1.02; Combined GWAS and replication P-value(GC)=0.00204, OR=0.95
|
No significant association was observed.
No significant association was observed.
|
Negative
|
rs8006348 |
TRIM9
|
A/G |
|
Primary GWAS P-value(GC)=0.0000491, OR=0.89; replication P-value(1-sided)=1, OR=1.05; Combined GWAS and replication P-value(GC)=0.0637, OR=0.95
|
No significant association was observed.
No significant association was observed.
|
Negative
|
rs875326 |
TNR
|
C/T |
|
Primary GWAS P-value(GC)=0.0000251, OR=1.15; replication P-value(1-sided)=0.183, OR=1.03; Combined GWAS and replication P-value(GC)=0.000111, OR=1.1
|
No significant association was observed.
No significant association was observed.
|
Negative
|
rs9371601 |
SYNE1
|
T/G |
|
genome-wide association: allele, OR(95%CI)=(1.21-1.10), P-value(raw)=4.3E-09, P-value(GC)=4.3E-08 for primary analysis
|
Significant association was found .
Significant association was found .
|
Positive
|
rs9804190 |
ANK3
|
C/T |
|
Primary GWAS P-value(GC)=0.0000306, OR=1.17; replication P-value(1-sided)=0.0963, OR=1.04; Combined GWAS and replication P-value(GC)=0.00012, OR=1.1
|
No significant association was observed.
No significant association was observed.
|
Negative
|
rs7296288 |
DHH
|
C/A |
|
genome-wide association: allele, OR(95%CI)=(1.20-1.09), P-value(raw)=9.4E-09, P-value(GC)=8.4E-08 for primary analysis
|
Significant association was found .
Significant association was found .
|
Positive
|
rs6746896 |
LMAN2L
CNNM4
|
A/G |
|
Primary GWAS P-value(GC)=0.00000233, OR=1.14; replication P-value(1-sided)=0.0386, OR=1.05; Combined GWAS and replication P-value(GC)=0.00000236, OR=1.1
|
Suggestive association was found.
Suggestive association was found.
|
Trend
|
rs6550435 |
TRANK1
|
G/T |
|
Primary GWAS P-value(GC)=0.0000197, OR=1.12; replication P-value(1-sided)=0.0326, OR=1.05; Combined GWAS and replication P-value(GC)=0.00000932, OR=1.09
|
Suggestive association was found.
Suggestive association was found.
|
Trend
|
rs6102917 |
PTPRT
|
C/G |
|
Primary GWAS P-value(GC)=0.0000388, OR=1.44; replication P-value(1-sided)=0.165, OR=1.11; Combined GWAS and replication P-value(GC)=0.0000846, OR=1.31
|
No significant association was observed.
No significant association was observed.
|
Negative
|
rs7827290 |
SLC45A4
|
G/T |
|
Primary GWAS P-value(GC)=0.0000354, OR=1.13; replication P-value(1-sided)=0.0167, OR=1.06; Combined GWAS and replication P-value(GC)=0.00000875, OR=1.1
|
Suggestive association was found.
Suggestive association was found.
|
Trend
|
rs780148 |
ZMIZ1
|
C/G |
|
Primary GWAS P-value(GC)=0.0000466, OR=1.12; replication P-value(1-sided)=0.23, OR=1.03; Combined GWAS and replication P-value(GC)=0.00014, OR=1.09
|
No significant association was observed.
No significant association was observed.
|
Negative
|
rs7578035 |
|
G/T |
|
Primary GWAS P-value(GC)=0.0000183, OR=1.12; replication P-value(1-sided)=0.0129, OR=1.06; Combined GWAS and replication P-value(GC)=0.00000277, OR=1.09
|
Suggestive association was found.
Suggestive association was found.
|
Trend
|
rs736408 |
ITIH3
|
C/T |
|
Primary GWAS P-value(GC)=0.00000122, OR=1.14; replication P-value(1-sided)=0.0465, OR=1.05; Combined GWAS and replication P-value(GC)=0.00000219, OR=1.1
|
Suggestive association was found.
Suggestive association was found.
|
Trend
|
rs3968 |
HNRNPA1P41
|
C/G |
|
Primary GWAS P-value(GC)=0.0000209, OR=1.17; replication P-value(1-sided)=1, OR=0.92; Combined GWAS and replication P-value(GC)=0.0174, OR=1.04
|
No significant association was observed.
No significant association was observed.
|
Negative
|
rs3845817 |
|
C/T |
|
Primary GWAS P-value(GC)=0.0000165, OR=0.9; replication P-value(1-sided)=0.00898, OR=0.94; Combined GWAS and replication P-value(GC)=0.00000176, OR=0.91
|
Suggestive association was found.
Suggestive association was found.
|
Trend
|
rs3774609 |
CACNA1D
|
G/T |
|
Primary GWAS P-value(GC)=0.0000114, OR=0.89; replication P-value(1-sided)=0.107, OR=0.97; Combined GWAS and replication P-value(GC)=0.0000373, OR=0.92
|
No significant association was observed.
No significant association was observed.
|
Negative
|
rs263906 |
|
C/T |
|
Primary GWAS P-value(GC)=0.0000242, OR=1.13; replication P-value(1-sided)=0.44, OR=1.01; Combined GWAS and replication P-value(GC)=0.000443, OR=1.08
|
No significant association was observed.
No significant association was observed.
|
Negative
|
rs4765913 |
CACNA1C
|
A/T |
|
Primary GWAS P-value(GC)=0.0000065, OR=1.15; replication P-value(1-sided)=0.00016, OR=1.13; Combined GWAS and replication P-value(GC)=0.0000000152, OR=1.14
|
Significant association was found in combined analysis .
Significant association was found in combined analysis .
|
Positive
|
rs4668059 |
STK39
|
C/T |
|
Primary GWAS P-value(GC)=0.0000445, OR=1.18; replication P-value(1-sided)=0.158, OR=1.04; Combined GWAS and replication P-value(GC)=0.000132, OR=1.12
|
No significant association was observed.
No significant association was observed.
|
Negative
|
rs4660531 |
|
G/T |
|
Primary GWAS P-value(GC)=0.0000316, OR=0.89; replication P-value(1-sided)=0.0111, OR=0.93; Combined GWAS and replication P-value(GC)=0.00000344, OR=0.91
|
Suggestive association was found.
Suggestive association was found.
|
Trend
|
rs4332037 |
MAD1L1
|
C/T |
|
Primary GWAS P-value(GC)=0.0000178, OR=0.87; replication P-value(1-sided)=0.03, OR=0.93; Combined GWAS and replication P-value(GC)=0.00000725, OR=0.9
|
Suggestive association was found.
Suggestive association was found.
|
Trend
|
rs17395886 |
FSTL5
|
A/C |
|
Primary GWAS P-value(GC)=0.0000218, OR=0.86; replication P-value(1-sided)=0.0351, OR=0.93; Combined GWAS and replication P-value(GC)=0.0000106, OR=0.89
|
Suggestive association was found.
Suggestive association was found.
|
Trend
|
rs2070615 |
CACNB3
|
A/G |
|
Primary GWAS P-value(GC)=0.00004, OR=0.9; replication P-value(1-sided)=0.00252, OR=0.93; Combined GWAS and replication P-value(GC)=0.00000102, OR=0.91
|
Suggestive association was found.
Suggestive association was found.
|
Trend
|
rs13245097 |
SNX8
|
C/T |
|
Primary GWAS P-value(GC)=0.0000381, OR=1.13; replication P-value(1-sided)=0.196, OR=1.02; Combined GWAS and replication P-value(GC)=0.000324, OR=1.08
|
No significant association was observed.
No significant association was observed.
|
Negative
|
rs16966413 |
SPRED1
|
A/G |
|
Primary GWAS P-value(GC)=0.0000474, OR=0.84; replication P-value(1-sided)=0.16, OR=0.95; Combined GWAS and replication P-value(GC)=0.0000997, OR=0.88
|
No significant association was observed.
No significant association was observed.
|
Negative
|
rs2281587 |
SH3PXD2A
|
C/T |
|
Primary GWAS P-value(GC)=0.0000196, OR=1.12; replication P-value(1-sided)=0.372, OR=1.01; Combined GWAS and replication P-value(GC)=0.000378, OR=1.07
|
No significant association was observed.
No significant association was observed.
|
Negative
|
rs2287921 |
RASIP1
|
C/T |
|
Primary GWAS P-value(GC)=0.0000168, OR=1.12; replication P-value(1-sided)=0.0137, OR=1.06; Combined GWAS and replication P-value(GC)=0.00000308, OR=1.1
|
Suggestive association was found.
Suggestive association was found.
|
Trend
|
rs2175420 |
TENM4
|
C/T |
|
Primary GWAS P-value(GC)=0.000029, OR=0.87; replication P-value(1-sided)=0.0078, OR=0.92; Combined GWAS and replication P-value(GC)=0.00000235, OR=0.89
|
Suggestive association was found.
Suggestive association was found.
|
Trend
|
rs2176528 |
|
C/G |
|
Primary GWAS P-value(GC)=0.0000398, OR=1.15; replication P-value(1-sided)=0.0104, OR=1.09; Combined GWAS and replication P-value(GC)=0.00000371, OR=1.12
|
Suggestive association was found.
Suggestive association was found.
|
Trend
|
rs11085829 |
NFIX
|
A/G |
|
Primary GWAS P-value(GC)=0.00000403, OR=0.87; replication P-value(1-sided)=0.175, OR=0.97; Combined GWAS and replication P-value(GC)=0.0000696, OR=0.92
|
No significant association was observed.
No significant association was observed.
|
Negative
|
rs11162405 |
GIPC2
DNAJB4
|
A/G |
|
Primary GWAS P-value(GC)=0.0000254, OR=0.9; replication P-value(1-sided)=0.0476, OR=0.96; Combined GWAS and replication P-value(GC)=0.0000182, OR=0.92
|
Suggestive association was found.
Suggestive association was found.
|
Trend
|
rs10896135 |
C11orf80
|
C/G |
|
Primary GWAS P-value(GC)=0.00000846, OR=0.88; replication P-value(1-sided)=0.00147, OR=0.91; Combined GWAS and replication P-value(GC)=0.000000156, OR=0.89
|
Suggestive association was found.
Suggestive association was found.
|
Trend
|
rs10994397 |
ANK3
|
C/T |
|
Primary GWAS P-value(GC)=0.00000000708, OR=0.74; replication P-value(1-sided)=0.116, OR=0.94; Combined GWAS and replication P-value(GC)=0.000000308, OR=0.82
|
Significant association was found.
Significant association was found.
|
Positive
|
rs12730292 |
|
C/G |
|
Primary GWAS P-value(GC)=0.0000237, OR=1.12; replication P-value(1-sided)=0.0171, OR=1.06; Combined GWAS and replication P-value(GC)=0.00000502, OR=1.1
|
Suggestive association was found.
Suggestive association was found.
|
Trend
|
rs12912251 |
C15orf53
|
G/T |
|
Primary GWAS P-value(GC)=0.00000957, OR=1.13; replication P-value(1-sided)=0.0204, OR=1.06; Combined GWAS and replication P-value(GC)=0.00000327, OR=1.1
|
Suggestive association was found.
Suggestive association was found.
|
Trend
|
rs11168751 |
CACNB3
DDX23
|
C/G |
|
Primary GWAS P-value(GC)=0.000018, OR=0.84; replication P-value(1-sided)=0.0143, OR=0.9; Combined GWAS and replication P-value(GC)=0.00000251, OR=0.86
|
Suggestive association was found.
Suggestive association was found.
|
Trend
|
rs12576775 |
TENM4
|
A/G |
|
Primary GWAS P-value(GC)=0.000000209, OR=0.85; replication P-value(1-sided)=0.00759, OR=0.92; Combined GWAS and replication P-value(GC)=0.000000044, OR=0.88
|
Significant association was found in combined analysis .
Significant association was found in combined analysis .
|
Positive
|