SNP Report

Basic Info

Name	rs2983517 dbSNP Ensembl
Location	chr6:165638243 - 165638243(1)
Variant Alleles	T/C
Ancestral Allele	T
Minor Allele	C
Minor Allele Frequence	0.189696
Functional Annotation	intron_variant; non_coding_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000366882, ENST00000539869, ENST00000580695); non_coding_transcript_variant(ENST00000580695)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
McDonald, M. L.,2012			chi square test:OR(95%CI) = 1.2(1.1â€“1.4),P-value = 0.001 f...... chi square test:OR(95%CI) = 1.2(1.1â€“1.4),P-value = 0.001 for BD-I More...	No significant association was observed. No significant association was observed.	Negative

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
PDE10A	phosphodiesterase 10A	6q26	1(0/1/0)

SNPs in LD with rs2983517 (count: 3) View in gBrowse (chr6:165638020..165647113 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs11755331	intron_variant; non_coding_transcript_variant	0.911[CEU]
rs2983516	intron_variant; non_coding_transcript_variant	1.0[TSI]
rs2983525	intron_variant; non_coding_transcript_variant	1.0[CEU]; 0.945[TSI]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)