BDgene

Core Gene from Gene Prioritization Pathways from PBA (Pathway-based Analysis) Enriched Pathways for Core Genes Enriched Pathways for Cross-disorder Genes

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GO Report

Basic Info

ID	GO:0006469
Name	negative regulation of protein kinase activity
Type	biological process
No. of Genes in BDgene	7
Source	Pathway by Database Search

PBA Result

GO related genes in BDgene (count: 7)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)	Evidence[PMID]
NF1	neurofibromin 1	17q11.2	1(1/0/0)	ISS
TRIB1	tribbles pseudokinase 1	8q24.13	1(0/0/1)	IMP[15299019]
CDKN2A	cyclin-dependent kinase inhibitor 2A	9p21	1(1/0/0)	IMP[15582998]
AKT1	v-akt murine thymoma viral oncogene homolog 1	14q32.33	3(3/0/0)	IMP[9373175]; ISS
PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	7q35-q36	1(1/0/0)	IDA[17255938]
IL6	interleukin 6	7p21-p15	1(0/1/0)	IEA
PPP1R1B	protein phosphatase 1, regulatory (inhibitor) subunit 1B	17q12	1(0/1/0)	TAS[10604473]