SNP Report

Basic Info

Name	rs2684953 dbSNP Ensembl
Location	chr15:34013530 - 34013530(1)
Variant Alleles	T/C
Ancestral Allele	C
Minor Allele	T
Minor Allele Frequence	0.460663
Functional Annotation	intron_variant; upstream_gene_variant.
Consequence to Transcript	intron_variant(ENST00000306730, ENST00000383263, ENST00000560035); upstream_gene_variant(ENST00000557872)
No. of Studies	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature
Overlap with SZ?	NO
Overlap with MDD?	NO

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result Category
Shi, J., 2007	C/T		TDT P-value = 0.86 of Allelic Association With Bipolar Disor...... TDT P-value = 0.86 of Allelic Association With Bipolar Disorder in the Combined Sample More...		Negative

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (Positive/Negative/Trend)
AVEN	apoptosis, caspase activation inhibitor	15q13.1	Mapped by Literature SNP
CHRM5	cholinergic receptor, muscarinic 5	15q26	1(0/1/0)

SNPs in LD with rs2684953 (count: 11) View in gBrowse (chr15:33983061..34028796 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Functional Annotation	r²[population]
rs6495448	intron_variant	0.902[TSI]
rs6495459	intron_variant	0.902[TSI]
rs8035125	intron_variant	0.869[TSI]
rs6495419	intron_variant	0.805[TSI]
rs2632076	intron_variant	1.0[CEU]
rs8039609	intron_variant	0.869[TSI]
rs2632075	intron_variant	1.0[CEU]; 0.935[TSI]
rs2684932	intron_variant	1.0[CEU]; 0.935[TSI]
rs2078562	intron_variant	1.0[CEU]
rs2702284	intron_variant	0.902[TSI]
rs2243858	intron_variant	1.0[CEU]

Overlap with SZ from cross-disorder studies (count: 0)

Overlap with MDD from cross-disorder studies (count: 0)